92724-29-3

Basic information

• Product Name: 2‐m‐tolylbenzofuran
• Synonyms: 2‐m‐tolylbenzofuran
• CAS NO: 92724-29-3
• Molecular Weight: 208.26
• Mol File: 92724-29-3.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: 2‐m‐tolylbenzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 2‐m‐tolylbenzofuran(92724-29-3)
• EPA Substance Registry System: 2‐m‐tolylbenzofuran(92724-29-3)

Safety Data

• Hazardous Substances Data: 92724-29-3(Hazardous Substances Data)

Upstream product

• 110252-67-0 2-(2-methoxy-phenyl)-3-oxo-3-m-tolyl-propionitrile 
• 1060684-36-7 2-(m-tolylethynyl)-O-triisopropylsilylphenol 
• 533-58-4 2-Iodophenol 
• 766-82-5 1-ethynyl-3-methyl-benzene 
• 98437-24-2 benzofuran-2-boronic acid 
• 625-95-6 3-Iodotoluene 
• 100-80-1 3-methylstyrene 
• 1380755-64-5 (E)-2-(3-methylstyryl)phenol 
• 15898-38-1 sodium 3-methylbenzenesulfinate 
• 91703-34-3 2-(β,β-dibromovinyl)phenol 
• 1620889-14-6 C₁₇H₁₆O₂ 
• 80778-47-8 1-iodo-2-methoxymethoxybenzene 
• 271-89-6 1-benzofurane 
• 108-41-8 1-chloro-3-methylbenzene 

Relevant articles and documents

Acid-promoted selective synthesis of trifluoromethylselenolated benzofurans with Se-(trifluoromethyl) 4-methylbenzenesulfonoselenoate

A Br?nsted acid-promoted trifluoromethylselenolation of benzofurans was disclosed by using Se-(trifluoromethyl) 4-methylbenzenesulfonoselenoate as a stable and easily prepared electrophilic trifluoromethylselenolating reagent. A wide range of SeCF3-substituted benzofuran derivatives were obtained in moderate to good yields with excellent regioselectivity. The tandem cyclization/trifluoromethylselenolation procedure of 1-methoxy-2-(arylethynyl)benzenes were also realized by engaging FeCl3 as the catalyst.

One-pot Tandem Heck alkynylation/cyclization reactions catalyzed by Bis(Pyrrolyl)pyridine based palladium pincer complexes

Ligand assisted palladium catalyzed one-pot tandem Heck alkynylation/cyclization reactions for the synthesis of benzofurans was reported in this paper. Well-defined palladium-pincer complexes exhibited excellent catalytic activities for the one-pot tandem Heck alkynylation/cyclization reactions yielding benzofuran derivatives using 0.1 molpercent catalyst. All the catalytic reactions are performed in air. The effects of variables such as solvents, the temperature on the catalytic activity are also reported. High product conversion was obtained for differently substituted 2-iodophenol at 120 °C in 10 h.

Synthesis of benzofurans from terminal alkynes and iodophenols catalyzed by recyclable palladium nanoparticles supported on N,O-dual doped hierarchical porous carbon under copper- and ligand-free conditions

We herein report that a stable and recyclable heterogeneous catalyst, consisting of Pd nanoparticles supported on N,O-dual doped hierarchical porous carbon derived from naturally available and renewable biomass-bamboo shoots, which allows for highly efficient one-pot tandem reaction of o-iodophenols with terminal alkynes to synthesize biologically active 2-benzofuran derivatives under copper- and ligand-free conditions. The catalyst performed superior catalytic performance compared with the analogous Pd/C and supported on other metal oxides under otherwise identical conditions. A broad set of aryl and alkyl terminal alkynes can be effectively coupled /cyclized with various o-iodophenols to afford their corresponding 2-benzofurans in good to high yields with good tolerance of multiple functional groups. Moreover, the catalyst showed good stability and could be reused several times without significant loss of activity.