928406-72-8

Basic information

• Product Name: [(S)-1-((R)-1-Amino-3-hydroxy-propylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester
• Synonyms: [(S)-1-((R)-1-Amino-3-hydroxy-propylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester
• CAS NO: 928406-72-8
• Molecular Weight: 371.436
• Mol File: 928406-72-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [(S)-1-((R)-1-Amino-3-hydroxy-propylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(S)-1-((R)-1-Amino-3-hydroxy-propylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester(928406-72-8)
• EPA Substance Registry System: [(S)-1-((R)-1-Amino-3-hydroxy-propylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester(928406-72-8)

Safety Data

• Hazardous Substances Data: 928406-72-8(Hazardous Substances Data)

Upstream product

• 1161-13-3 N-Cbz-L-Phe 
• 928406-70-6 {(S)-1-[(R)-3-(tert-Butyl-diphenyl-silanyloxy)-1-carbamoyl-propylcarbamoyl]-2-phenyl-ethyl}-carbamic acid benzyl ester 
• 928406-68-2 (R)-2-((S)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-4-hydroxy-butyric acid 
• 928406-69-3 [(S)-1-((R)-1-Carbamoyl-3-hydroxy-propylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester 
• 928406-71-7 {(S)-1-[(R)-1-Amino-3-(tert-butyl-diphenyl-silanyloxy)-propylcarbamoyl]-2-phenyl-ethyl}-carbamic acid benzyl ester 

Downstream Products

• 928406-62-6 ((S)-1-{(2S,4S)-2-[Bis-(2-chloro-ethyl)-amino]-2-oxo-2λ⁵-[1,3,2]oxazaphosphinan-4-ylcarbamoyl}-2-phenyl-ethyl)-carbamic acid benzyl ester 
• 928406-63-7 ((S)-1-{(2R,4S)-2-[Bis-(2-chloro-ethyl)-amino]-2-oxo-2λ⁵-[1,3,2]oxazaphosphinan-4-ylcarbamoyl}-2-phenyl-ethyl)-carbamic acid benzyl ester 
• 5241-56-5 benzyl [(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]carbamate 

Relevant articles and documents

Phenylalanyl-aminocyclophosphamides as model prodrugs for proteolytic activation: Synthesis, stability, and stereochemical requirements for enzymatic cleavage

4-Aminocyclophosphamide (4-NH2-CPA, 7) was proposed as a prodrug moiety of phosphoramide mustard. Four diastereomers of phenylalanine-conjugates of 4-NH2-CPA were synthesized and their stereochemistry was assigned based on chromatogr