933055-19-7

Basic information

• Product Name: tert-butyl (3aR,4R,6aS)-4-{[(tert-butyldiphenylsilyl)oxy]methyl}-2,2-dimethyltetrahydro-5H-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylate
• Synonyms: tert-butyl (3aR,4R,6aS)-4-{[(tert-butyldiphenylsilyl)oxy]methyl}-2,2-dimethyltetrahydro-5H-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylate
• CAS NO: 933055-19-7
• Molecular Weight: 511.734
• Mol File: 933055-19-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl (3aR,4R,6aS)-4-{[(tert-butyldiphenylsilyl)oxy]methyl}-2,2-dimethyltetrahydro-5H-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (3aR,4R,6aS)-4-{[(tert-butyldiphenylsilyl)oxy]methyl}-2,2-dimethyltetrahydro-5H-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylate(933055-19-7)
• EPA Substance Registry System: tert-butyl (3aR,4R,6aS)-4-{[(tert-butyldiphenylsilyl)oxy]methyl}-2,2-dimethyltetrahydro-5H-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylate(933055-19-7)

Safety Data

• Hazardous Substances Data: 933055-19-7(Hazardous Substances Data)

Upstream product

• 34619-03-9 tert-butyldicarbonate 
• 51372-93-1 (S)-tert-butyl (1-hydroxy-4-(methylthio)butan-2-yl)carbamate 
• 354153-37-0 1,1-dimethylethyl [(1S)-1-({[(1,1-dimethylethyl)(diphenyl)silyl]oxy}methyl)prop-2-en-1-yl]carbamate 
• 205444-34-4 (S)-tert-butyl 2-(hydroxymethyl)-2,5-dihydro-1H-pyrrole-1-carboxylate 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 24424-99-5 di-tert-butyl dicarbonate 
• 920009-47-8 (2S,3S)-3-(N-allyl-N-tert-butoxycarbonyl)amino-4-pentene-1,2-diol 
• 852616-64-9 tert-butyl (S)-2-{[(tert-butyldiphenylsilyl)oxy]methyl}-2,5-dihydro-1H-pyrrole-1-carboxylate 
• 852616-66-1 tert-butyl (2R,3R,4S)-2-{[(tert-butyldiphenylsilyl)oxy]methyl}-3,4-dihydroxypyrrolidine-1-carboxylate 
• 77-76-9 2,2-dimethoxy-propane 

Downstream Products

• 117781-12-1 (2R,3R,4S)-3,4-dihydroxy-2-hydroxymethylpyrrolidine hydrochloride 

Relevant articles and documents

Enantioselective synthesis of hydroxylated pyrrolidines via Sharpless epoxidation and olefin metathesis

The enantioselective synthesis of polyhydroxylated pyrrolidines from enantiomerically pure 2,3-epoxy-pent-4-en-1-ol 5 is described herein. The epoxy alcohol, readily available in any configuration by Sharpless epoxidation, was submitted to regioselective C-3 ring-opening with allyl amine, Boc-protection and ring-closing metathesis to yield dehydropyrrole derivative 7. From this key intermediate, 1,4-dideoxy-1,4-imino-d-ribitol (+)-3 and 1,4-dideoxy-1,4-imino-d-allitol (+)-4 were prepared in high yields. The enantiomers of these compounds can be obtained by the same sequence starting from an epoxy alcohol with the opposite configuration.