938-81-8

Basic information

• Product Name: N-nitrosoacetanilide
• Synonyms: N-nitrosoacetanilide;N-Nitroso-N-phenylacetamide
• CAS NO: 938-81-8
• Molecular Formula: C₈H₈N₂O₂
• Molecular Weight: 164.16
• Mol File: 938-81-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 51°C (rough estimate)
• Boiling Point: 291.62°C (rough estimate)
• Flash Point: 99.7°C
• Appearance: /
• Density: 1.2739 (rough estimate)
• Vapor Pressure: 0.0361mmHg at 25°C
• Refractive Index: 1.6000 (estimate)
• CAS DataBase Reference: N-nitrosoacetanilide(CAS DataBase Reference)
• NIST Chemistry Reference: N-nitrosoacetanilide(938-81-8)
• EPA Substance Registry System: N-nitrosoacetanilide(938-81-8)

Safety Data

• Hazardous Substances Data: 938-81-8(Hazardous Substances Data)

Usage

Description

N-nitrosoacetanilide is a chemical compound that serves as a synthesis intermediate, a nitric oxide-donor, and an oxidizer in radical processes. It is known for its ability to generate nitric oxide, which has various applications in different industries.

Uses

Used in Pharmaceutical Industry:
N-nitrosoacetanilide is used as a synthesis intermediate for the production of various pharmaceutical compounds. Its role in the synthesis process is crucial for creating drugs with specific therapeutic properties.
Used in Nitric Oxide Research:
As a nitric oxide-donor, N-nitrosoacetanilide is used in research to study the effects of nitric oxide on biological systems. Nitric oxide is a signaling molecule that plays a vital role in various physiological processes, and understanding its role can lead to the development of new treatments for various diseases.
Used in Chemical Reactions:
N-nitrosoacetanilide is used as an oxidizer in radical processes, which are essential for various chemical reactions. Its ability to generate reactive species can help drive reactions to completion, making it a valuable component in the synthesis of certain chemicals.

Safety Profile

Many N-nitroso compounds arecarcinogens. Explodes on contact with piperidine. Mixturewith thiophene explodes at room temperature. Whenheated to decomposition it emits toxic fumes of NOx. Seealso N-NITROSO COMPOUNDS.

InChI:InChI=1/C8H8N2O2/c1-7(11)10(9-12)8-5-3-2-4-6-8/h2-6H,1H3

Upstream product

• 2684-02-8 benzenediazonium 
• 108-24-7 acetic anhydride 
• 7782-77-6 cis-nitrous acid 
• 103-84-4 Acetanilid 

Downstream Products

• 71-43-2 benzene 
• 2404-87-7 3-phenylthiophene 
• 825-55-8 2-phenylthiophene 
• 1008-88-4 3-phenylpyridine 
• 1008-89-5 2-phenylpyridine 
• 939-23-1 p-phenylpyridine 
• 69217-15-8 (E)-1-methyl-2-(phenyldiazenyl)-1H-pyrrole 
• 15719-64-9 methylammonium carbonate 
• 882-33-7 diphenyldisulfane 
• 108-90-7 chlorobenzene 
• 93289-20-4 1-ethoxycarbonyl-2-phenylpyrrole 
• 108-86-1 bromobenzene 
• 2052-07-5 2-Bromobiphenyl 
• 92-66-0 4-bromo-1,1'-biphenyl 

Relevant articles and documents

A simple and efficient method for the N-nitrosation of secondary amines with NaNO2-Ac2O under mild conditions

Secondary amines can be easily converted into their corresponding nitroso derivations using NaNO2-Ac2O as a nitrosating agent in dichloromethane at room temperature with high yields.

Ein neuer Weg zu aromatischen Diazocyaniden

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