943726-01-0 Usage
Description
Propargyl-PEG3-Ms is a crosslinking reagent that features a propargyl group and a mesyl group. It is designed to participate in copper-catalyzed Click Chemistry reactions, where the propargyl group reacts with azide-bearing compounds or biomolecules, facilitating the formation of stable triazole linkages.
Uses
Used in Bioconjugation:
Propargyl-PEG3-Ms is used as a bioconjugation agent for the selective and efficient attachment of azide-containing biomolecules. This is particularly useful in the development of targeted drug delivery systems, biosensors, and other bioanalytical applications.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Propargyl-PEG3-Ms is utilized as a component in the design of drug delivery systems. Its ability to form stable linkages with azide-modified drugs or drug carriers allows for the creation of more effective and targeted therapies.
Used in Materials Science:
In the field of materials science, Propargyl-PEG3-Ms is employed as a crosslinking agent to create new materials with specific properties. The stable triazole linkages formed through Click Chemistry can enhance the mechanical, chemical, or biological characteristics of the resulting materials.
Used in Chemical Synthesis:
Propargyl-PEG3-Ms serves as a versatile building block in chemical synthesis, enabling the creation of complex organic molecules with potential applications in various industries, including pharmaceuticals, agrochemicals, and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 943726-01-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,3,7,2 and 6 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 943726-01:
(8*9)+(7*4)+(6*3)+(5*7)+(4*2)+(3*6)+(2*0)+(1*1)=180
180 % 10 = 0
So 943726-01-0 is a valid CAS Registry Number.
943726-01-0Relevant articles and documents
Synthesis and structure-activity relationship studies of conformationally flexible tetrahydroisoquinolinyl triazole carboxamide and triazole substituted benzamide analogues as σ2 receptor ligands
Bai, Suping,Li, Shihong,Xu, Jinbin,Peng, Xin,Sai, Kiran,Chu, Wenhua,Tu, Zhude,Zeng, Chenbo,Mach, Robert H.
supporting information, p. 4239 - 4251 (2014/06/09)
Two novel classes of compounds targeting the sigma-2 (σ2) receptor were synthesized, and their bioactivities to binding σ1 and σ2 receptors were measured. Four novel triazole carboxamide analogues, 24d, 24e, 24f, and 39c, demonstrated high affinity and selectivity for the σ2 receptor. These data suggest 11C-labeled versions of these compounds may be potential σ2-selective radiotracers for imaging the proliferative status of solid tumors.
