943749-58-4

Basic information

• Product Name: 8-bromo-1,2-dihydroisoquinolin-3(4H)-one
• Synonyms: 8-bromo-1,2-dihydroisoquinolin-3(4H)-one;8-Bromo-1,4-dihydro-2H-isoquinolin-3-one;8-bromo-1,4-dihydroisoquinolin-3(2H)-one
• CAS NO: 943749-58-4
• Molecular Formula: C9H8BrNO
• Molecular Weight: 226.06992
• Mol File: 943749-58-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 8-bromo-1,2-dihydroisoquinolin-3(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 8-bromo-1,2-dihydroisoquinolin-3(4H)-one(943749-58-4)
• EPA Substance Registry System: 8-bromo-1,2-dihydroisoquinolin-3(4H)-one(943749-58-4)

Safety Data

• Hazardous Substances Data: 943749-58-4(Hazardous Substances Data)

Usage

Description

8-bromo-1,2-dihydroisoquinolin-3(4H)-one is a chemical compound with the molecular formula C9H9BrNO, belonging to the isoquinoline family. It is recognized for its potential as a building block in organic synthesis and medicinal chemistry research, and is valued for its diverse biological activities, such as antitumor, anti-inflammatory, and antimicrobial properties. 8-bromo-1,2-dihydroisoquinolin-3(4H)-one is of significant interest in drug development and chemical biology studies, with its chemical properties and biological effects being crucial for researchers and scientists to explore its potential therapeutic applications.

Uses

Used in Pharmaceutical Research:
8-bromo-1,2-dihydroisoquinolin-3(4H)-one is used as a key building block in the development of new pharmaceuticals due to its versatile chemical structure and demonstrated biological activities. Its antitumor properties make it a promising candidate for the creation of anticancer drugs, while its anti-inflammatory and antimicrobial effects suggest potential applications in treating inflammatory and infectious diseases.
Used in Organic Synthesis:
In the field of organic synthesis, 8-bromo-1,2-dihydroisoquinolin-3(4H)-one serves as an important intermediate for the synthesis of various complex organic molecules. Its unique structure allows for multiple synthetic pathways, facilitating the creation of a wide range of compounds with different therapeutic and industrial applications.
Used in Medicinal Chemistry:
8-bromo-1,2-dihydroisoquinolin-3(4H)-one is utilized as a starting material in medicinal chemistry for the design and synthesis of novel bioactive molecules. Its ability to exhibit multiple biological activities makes it a valuable component in the development of drugs targeting various diseases and conditions.
Used in Chemical Biology Studies:
In chemical biology, 8-bromo-1,2-dihydroisoquinolin-3(4H)-one is employed to study the interactions between small molecules and biological targets. Understanding these interactions can lead to the discovery of new drug targets and the development of more effective therapeutic agents.
Used in Drug Development:
8-bromo-1,2-dihydroisoquinolin-3(4H)-one is used as a potential lead compound in drug development. Its demonstrated biological activities and chemical properties make it a candidate for further optimization and development into effective pharmaceuticals for treating a variety of diseases.
Used in Antitumor Applications:
8-bromo-1,2-dihydroisoquinolin-3(4H)-one is used as an antitumor agent for its potential to inhibit the growth and proliferation of cancer cells. Its application in this area is driven by the need for new and effective treatments against various types of cancer.
Used in Anti-inflammatory Applications:
8-bromo-1,2-dihydroisoquinolin-3(4H)-one is used as an anti-inflammatory agent, leveraging its ability to reduce inflammation and alleviate symptoms associated with inflammatory conditions.
Used in Antimicrobial Applications:
8-bromo-1,2-dihydroisoquinolin-3(4H)-one is used as an antimicrobial agent to combat microbial infections, highlighting its potential in the development of new antibiotics and antifungal agents.

Upstream product

• 846032-36-8 4-bromo-1,3-dihydro-2H-inden-2-one 
• 50-00-0 formaldehyd 
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Relevant articles and documents

COMPOUNDS AND USES THEREOF

The present invention features compounds useful in the treatment of adenosine or adenosine receptor related disorders.

SUBSTITUTED DIHYDROISOQUINOLINONE AND ISOQUINOLINEDIONE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS

A series of disubstituted dihydroisoquinolinone and isoquinolinedione derivatives represented by Formula I, or pharmaceutically acceptable salts thereof are presented. Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more other therapeutically active compounds, and a pharmaceutically acceptable carrier. Methods of treating conditions associated with, or caused by, calcium channel activity, including, for example, acute pain, chronic pain, visceral pain, inflammatory pain, neuropathic pain, urinary incontinence, itchiness, allergic dermatitis, epilepsy, diabetic neuropathy, irritable bowel syndrome, depression, anxiety, multiple sclerosis, sleep disorder, bipolar disorder and stroke, comprise administering an effective amount of the present compounds, either alone, or in combination with one or more other therapeutically active compounds.