94435-76-4Relevant articles and documents
Nickel-Catalyzed Thiolation of Aryl Nitriles
Delcaillau, Tristan,Morandi, Bill
supporting information, p. 11823 - 11826 (2021/07/16)
A nickel-catalyzed thiolation of aryl nitriles has been developed to access functionalized aryl thioethers. The ligand dcype (1,2-bis(dicyclohexylphosphino)ethane) as well as the base KOtBu (potassium tert-butoxide) are essential to achieve this transformation. This scalable and practical process involves both a C?C bond activation and a C?S bond formation. Furthermore, this reaction shows a high functional-group tolerance and enables the late-stage functionalization of important molecules.
Manganese-catalyzed cross-coupling of thiols with aryl iodides
Liu, Tsung-Jui,Yi, Chih-Lun,Chan, Chien-Ching,Lee, Chin-Fa
, p. 1029 - 1034 (2013/08/25)
A manganese-catalyzed cross-coupling reaction of thiols with aryl iodides, furnishing aryl thioethers in good to excellent yields has been reported; the system shows good functional group tolerance and enables the sterically demanding aryl iodides to couple with thiols. Coming up for ArI: A manganese-catalyzed cross-coupling reaction of thiols with aryl iodides that furnishes aryl thioethers in good to excellent yields has been reported. Functional groups such as unprotected alcohols and chloro substituents are tolerated under these reaction conditions. Moreover, this catalytic system enables the sterically demanding aryl iodides to couple with thiols (see scheme; R=aryl or alkyl).
A general rhodium-catalyzed cross-coupling reaction of thiols with aryl iodides
Lai, Chih-Shin,Kao, Hsin-Lun,Wang, Yan-Jhang,Lee, Chin-Fa
supporting information; experimental part, p. 4365 - 4367 (2012/09/22)
The general procedure for the rhodium-catalyzed cross-coupling of thiols with aryl iodides is described. The catalytic system consists of 5 mol % of [RhCl(cod)]2 and 10 mol % of PPh3 as a ligand. A variety of aryl iodides reacted with thiols, giving aryl thioethers in good to excellent yields. It is important to note that the deactivated aryl iodides such as 4-iodoanisole is worked smoothly to provide the corresponding aryl thioethers in excellent yields. Functional groups such as free-amines, chloro, are all tolerated under the employed reaction conditions.