94664-76-3

Basic information

• Product Name: (Z)-N-(benzylidene)-p-methoxy-phenylamine N-oxide
• CAS NO: 94664-76-3
• Molecular Weight: 227.263
• Mol File: 94664-76-3.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: (Z)-N-(benzylidene)-p-methoxy-phenylamine N-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-N-(benzylidene)-p-methoxy-phenylamine N-oxide(94664-76-3)
• EPA Substance Registry System: (Z)-N-(benzylidene)-p-methoxy-phenylamine N-oxide(94664-76-3)

Safety Data

• Hazardous Substances Data: 94664-76-3(Hazardous Substances Data)

Upstream product

• 4546-20-7 p-methoxyphenylhydroxylamine 
• 100-52-7 benzaldehyde 
• 17377-95-6 benzyl(4-methoxyphenyl)amine 
• 100-17-4 para-methoxynitrobenzene 
• 1516-21-8 4-methoxynitrosobenzene 
• 544-25-2 Cyclohepta-1,3,5-triene 
• 97369-36-3 1,2,3,5-Tetrahydro-7-methyl-2-phenyl-3-phenylsulfonyl-4H-1-benzazepin-4-on 
• 19064-77-8 C-phenyl-N-p-tolyl-nitrone 
• 2876-13-3 N-benzylpyridinium chloride 
• 98-95-3 nitrobenzene 
• 1137-96-8 N-(benzylidene)aniline N-oxide 
• 104-94-9 4-methoxy-aniline 

Downstream Products

• 1040389-88-5 C₂₆H₂₄N₂O₄ 
• 153463-27-5 (R)-3-[(3R,4S)-1-(4-Methoxy-phenyl)-2-oxo-4-phenyl-azetidin-3-yl]-4-phenyl-oxazolidin-2-one 
• 1215859-41-8 C₂₉H₂₇NO₆ 
• 1215859-43-0 C₃₀H₂₉NO₆ 
• 1228016-74-7 5,7a-di(tert-butyl)-3-(4-methoxyphenyl)-2-phenyl-2,3,3a,7a-tetrahydro-1,2-benzisoxazole-4,7-dione 
• 1402404-09-4 (4S,10aS)-3-(4-methoxyphenyl)-1,1-dimethyl-4-phenyl-3,4,10,10a-tetrahydro-1H-indeno[1,2-e][1,2]oxazepine 
• 1403981-64-5 (E)-2-(2-(benzylideneamino)-5-methoxyphenyl)-N-methyl-N-tosylacetamide 
• 65836-82-0 1-benzyl-2,3-dihydro-5-methoxy-1H-indol-2-one 
• 1312924-36-9 ethyl 5-methoxy-2-phenyl-1H-indole-3-carboxylate 
• 19340-68-2 1-(4-methoxy-phenyl)-4-phenyl-azetidin-2-one 
• 783-08-4 [4-(benzylideneamino)phenyl]methanol 

Relevant articles and documents

Gold Catalysts Can Generate Nitrone Intermediates from a Nitrosoarene/Alkene Mixture, Enabling Two Distinct Catalytic Reactions: A Nitroso-Activated Cycloheptatriene/Benzylidene Rearrangement

Gold-catalyzed reactions of cycloheptatrienes with nitrosoarenes yield nitrone derivatives efficiently. This reaction sequence enables us to develop gold-catalyzed aerobic oxidations of cycloheptatrienes to afford benzaldehyde derivatives using CuCl and nitrosoarenes as co-catalysts (10-30 mol %). Our density functional theory calculations support a novel nitroso-activated rearrangement, tropylium → benzylidene. With the same nitrosoarenes, we developed their gold-catalyzed [2 + 2 + 1]-annulations between nitrosobenzene and two enol ethers to yield 5-alkoxyisoxazolidines using 1,4-cyclohexadienes as hydrogen donors.

Polyfunctionalized biaryls accessed by a one-pot nucleophilic aromatic substitution and sigmatropic rearrangement reaction cascade under mild conditions

A practical synthetic method has been developed for polyfunctionalized biaryls based on a facile one-pot nucleophilic aromatic substitution (SNAr) reaction and [5,5]- or [3,3]-sigmatropic rearrangement reaction cascade. Under mild basic conditions, N-arylhydroxylamines reacted with o-activated fluoro (het)arenes to form N,O-diarylhydroxylamine intermediates which underwent spontaneously selective [5,5]-sigmatropic rearrangement reaction to produce diverse functionalized 4-amino-4′-hydroxy-1,1′-biaryls. A sequential SNAr reaction and [3,3]-sigmatropic rearrangement took place between N-arylhydroxylamines and 2-fluoropyridine derivatives or 4-fluorobenzonitrile to afford functionalized 2-amino-2′-hydroxy-1,1′-biaryls. As invaluable and unique building blocks, the resulting biaryls were applied in the straightforward synthesis of N2,O2-coronarene, carbazole, aza- and diaza carbazole derivatives.

Tandem Chiral Cu(II) Phosphate-Catalyzed Deoxygenation of Nitrones/Enantioselective Povarov Reaction with Enecarbamates

A new catalytic enantioselective tandem deoxygenation/aza-Diels-Alder reaction of nitrones with enecarbamates was serendipitously discovered in the presence of chiral copper(II) diphosphate complexes. This process affords a wide range of 4-aminotetrahydroquinolines in respectable yields under mild conditions with good to excellent ee values.