94743-27-8

Basic information

• Product Name: 3-Heptanone, 2,2-dimethyl-7-phenyl-
• CAS NO: 94743-27-8
• Molecular Formula: C15H22O
• Molecular Weight: 218.339
• Mol File: 94743-27-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Heptanone, 2,2-dimethyl-7-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Heptanone, 2,2-dimethyl-7-phenyl-(94743-27-8)
• EPA Substance Registry System: 3-Heptanone, 2,2-dimethyl-7-phenyl-(94743-27-8)

Safety Data

• Hazardous Substances Data: 94743-27-8(Hazardous Substances Data)

Upstream product

• 507-19-7 t-butyl bromide 
• 2270-20-4 5-Phenylpentanoic acid 
• 75-97-8 3,3-dimethyl-butan-2-one 
• 104-52-9 phenylpropyl chloride 

Downstream Products

• 95546-23-9 4-Dimethylaminomethyl-2,2-dimethyl-7-phenyl-heptan-3-one 
• 94743-23-4 1-[3,3-Dimethyl-2-oxo-1-(3-phenyl-propyl)-butyl]-3-(2,3-dimethyl-phenyl)-1H-quinazoline-2,4-dione 
• 94743-44-9 4-Imidazol-1-yl-2,2-dimethyl-7-phenyl-heptan-3-one 
• 95546-27-3 4-Imidazol-1-ylmethyl-2,2-dimethyl-7-phenyl-heptan-3-one 
• 94743-18-7 4-Dimethylamino-2,2-dimethyl-7-phenyl-heptan-3-one 
• 94743-40-5 4-Bromo-2,2-dimethyl-7-phenyl-heptan-3-one 

Relevant articles and documents

Ni-catalyzed reductive coupling of alkyl acids with unactivated tertiary alkyl and glycosyl halides

This work highlights Ni-catalyzed reductive coupling of alkyl acids with alkyl halides, particularly sterically hindered unactivated tertiary alkyl bromides for the production of all carbon quaternary ketones. The reductive strategy is applicable to α-selective synthesis of saturated, fully oxygenated C-acyl glycosides through easy manipulations of the readily available sugar bromides and alkyl acids, avoiding otherwise difficult multistep conversions. Initial mechanistic studies suggest that a radical chain mechanism (cycle B, Scheme 1) may be plausible, wherein MgCl2 promotes the reduction of NiII complexes.