95388-12-8

Basic information

• Product Name: 1H-1,4,7-Triazonine, 1,1'-(1,2-ethanediyl)bis[octahydro-4,7-bis[(4-methylphenyl)sulfonyl]-
• CAS NO: 95388-12-8
• Molecular Formula: C42H56N6O8S4
• Molecular Weight: 901.206
• Mol File: 95388-12-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1H-1,4,7-Triazonine, 1,1'-(1,2-ethanediyl)bis[octahydro-4,7-bis[(4-methylphenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1,4,7-Triazonine, 1,1'-(1,2-ethanediyl)bis[octahydro-4,7-bis[(4-methylphenyl)sulfonyl]-(95388-12-8)
• EPA Substance Registry System: 1H-1,4,7-Triazonine, 1,1'-(1,2-ethanediyl)bis[octahydro-4,7-bis[(4-methylphenyl)sulfonyl]-(95388-12-8)

Safety Data

• Hazardous Substances Data: 95388-12-8(Hazardous Substances Data)

Upstream product

• 52667-89-7 N,N',N-tris(p-toluenesulfonyl)-1,4,7-triazacyclononane 
• 1354021-90-1 1,4-di(tosyl)-1,4,7-triazacyclononane tosylate 
• 106-93-4 ethylene dibromide 
• 386218-02-6 N,N'-bis(p-toluenesulfonyl)-1,4,7-triazacyclononane hydrobromide 
• 6315-52-2 1,2-bis-tosyloxyethane 
• 56234-52-7 1,8-bis(p-toluenesulfonyloxy)-3,6-bis(p-toluenesulfonyl)-3,6-diazaoctane 
• 107-15-3 ethylenediamine 

Downstream Products

• 1056967-99-7 1,2-Bis(4-p-toluenesulfonyl-1,4,7-triazacyclonon-1-yl)ethane 

Relevant articles and documents

1,2-BIS-(4,7-DIMETHYL-1,4,7-TRIAZACYCLONON-1-YL)-ETHANE AND INTERMEDIATE THEREOF

The present invention provides improved processes for the synthesis of 1,4-ditosyl- 1,4,7-triazacyclonone and protected analogues thereof, and to synthesise bis(triazacyclononane) ligands.

Complexes of cyclic polyaza chelators with cations of alkaline earth metals for enhanced biological activity

Cyclic polyaza chelators that possess high affinity and specificity for first transition series metal cations exhibit an unanticipated improvement in biological activity when administered as complexes with cations of the alkaline earth metals, Ca(II) and Mg(II), most notably Ca(II). By virtue of this improvement, these complexes are particularly effective in the treatment of pathological conditions, including ischemia and ischemia-reperfusion injury.