955959-45-2Relevant articles and documents
Total synthesis of neooxazolomycin
Onyango, Evans Otieno,Tsurumoto, Joji,Imai, Naoko,Takahashi, Keisuke,Ishihara, Jun,Hatakeyama, Susumi
, p. 6703 - 6705 (2008/09/18)
Two sides to the story: Neooxazolomycin, a member of the oxazolomycin family of antibiotics, was synthesized in naturally occurring form by a convergent approach. This highly stereoselective strategy consists of a Tamao hydrosilylation, palladium-catalyzed enolate alkenylation, dihydroxylation accompanied by lactonization, and a Nozaki-Hiyama-Kishi reaction to construct the right-hand segment as well as an improved route to the left-hand segment. (Chemical Equation Presented).