95785-28-7

Basic information

• Product Name: Ethanone, 1-[4-(3-hydroxy-3-methyl-1-butynyl)phenyl]-
• Synonyms: 1-(4-(3-hydroxy-3-methylbut-1-yn-1-yl)phenyl)ethanone;1-(4-(3-hydroxy-3-methylbut-1-ynyl)phenyl)ethanone;2-methyl-4-(4'-acetyl)phenyl-3-butyn-2-ol;Ethanone,1-[4-(3-hydroxy-3-methyl-1-butynyl)phenyl];4-(3-hydroxy-3-methylbut-1-ynyl)acetophenone;4-[4-(3-hydroxy-3-methyl-1-butynyl)-phenyl]-1-ethanone
• CAS NO: 95785-28-7
• Molecular Formula: C13H14O2
• Molecular Weight: 202.253
• Mol File: 95785-28-7.mol
• Article Data: 26

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[4-(3-hydroxy-3-methyl-1-butynyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[4-(3-hydroxy-3-methyl-1-butynyl)phenyl]-(95785-28-7)
• EPA Substance Registry System: Ethanone, 1-[4-(3-hydroxy-3-methyl-1-butynyl)phenyl]-(95785-28-7)

Safety Data

• Hazardous Substances Data: 95785-28-7(Hazardous Substances Data)

Upstream product

• 99-90-1 para-bromoacetophenone 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 13329-40-3 4-Iodoacetophenone 
• 264135-62-8 1,1,2,2,3,3,4,4,4-nonafluoro-butane-1-sulfonic acid 4-acetyl-phenyl ester 
• 99-93-4 4-Hydroxyacetophenone 

Downstream Products

• 42472-69-5 4-ethynylacetophenone 
• 123770-67-2 1-(4-((4-methoxyphenyl)ethynyl)phenyl)ethanone 
• 1228390-96-2 1-(4-(3-(4-methoxyphenyl)-3-methylbut-1-ynyl)phenyl)ethanone 
• 1415694-17-5 1-(4-(1,1-dimethyl-3-phenyl-1H-indeno[1,2-c]furan-8-yl)phenyl)ethanone 
• 1448750-51-3 C₁₃⁽¹³⁾CH₁₄O₄ 
• 1515880-58-6 1-(4-(9,9-dimethyl-9H-benzo[b]pyrrolo[1,2-d][1,2,3]triazolo[5,1-g][1,4]diazepin-8-yl)phenyl)ethanone 
• 1515880-67-7 1-(4-(1,3,9,9-tetramethyl-9H-benzo[b]pyrrolo[1,2-d][1,2,3]triazolo[5,1-g][1,4]diazepin-8-yl)phenyl)ethanone 
• 1549706-28-6 diisopropyl ((4-acetylphenyl)ethynyl)phosphonate 
• 1174920-00-3 (E)-1-(4-(3-hydroxy-3-methylbut-1-en-1-yl)phenyl)ethan-1-one 
• 72390-25-1 1-(4-(3-hydroxy-3-methylbutyl)phenyl)ethan-1-one 

Relevant articles and documents

Hydrazine Hydrate Accelerates Neocuproine–Copper Complex Generation and Utilization in Alkyne Reduction, a Significant Supplement Method for Catalytic Hydrogenation

Diimine (HN═NH) is a strong reducing agent, but the efficiency of diimine oxidized from hydrazine hydrate or its derivatives is still not good enough. Herein, we report an in situ neocuproine–copper complex formation method. The redox potential of this complex enable it can serve as an ideal redox catalyst in the synthesis of diimine by oxidation of hydrazine hydrate, and we successfully applied this technique in the reduction of alkynes. This reduction method displays a broad functional group tolerance and substrate adaptability as well as the advantages of safety and high efficiency. Especially, nitro, benzyl, boc, and sulfur containing alkynes can be reduced to the corresponding alkanes directly, which provides a useful complementary method to traditional catalytic hydrogenation. Besides, we applied this method in the preparation of the Alzheimer’s disease drug CT-1812 and studied the mechanism.

Palladium-Catalyzed Nitration of Meyer-Schuster Intermediates with tBuONO as Nitrogen Source at Ambient Temperature

A novel domino palladium-catalyzed nitration of Meyer-Schuster intermediates which were generated in situ from propargylic alcohols was developed, by the use of t-BuONO, leading to α-nitro enones in good to excellent yields at room temperature with a broa

Palladium-catalyzed oxidative deacetonative coupling of 4-aryl-2-methyl-3-butyn-2-ols with H-phosphonates

An efficient and generally applicable protocol for palladium-catalyzed oxidative deacetonative coupling of 4-aryl-2-methyl-3-butyn-2-ols with dialkyl H-phosphonates has been developed. This methodology provides a new and practical route to alkynylphosphonates using the inexpensive 4-aryl-2-methyl-3-butyn-2-ols as the alkyne sources. This reaction could also be performed with aryl bromides, 2-methyl-3-butyne-2-ol and dialkyl H-phosphonates using the cheap 2-methyl-3-butyne-2-ol as an alkyne source. This journal is