965-01-5

Basic information

• Product Name: 3-(4-methoxyphenyl)-3-oxo-N-phenylpropanamide
• Synonyms: 3-(4-methoxyphenyl)-3-oxo-N-phenylpropanamide
• CAS NO: 965-01-5
• Molecular Weight: 269.3
• Mol File: 965-01-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 3-(4-methoxyphenyl)-3-oxo-N-phenylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-methoxyphenyl)-3-oxo-N-phenylpropanamide(965-01-5)
• EPA Substance Registry System: 3-(4-methoxyphenyl)-3-oxo-N-phenylpropanamide(965-01-5)

Safety Data

• Hazardous Substances Data: 965-01-5(Hazardous Substances Data)

Upstream product

• 19226-36-9 3-phenyl-5H-1,4,2-dioxazol-5-one 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 495-18-1 Benzohydroxamic acid 
• 100-09-4 4-methoxybenzoic acid 
• 100-65-2 N-Phenylhydroxylamine 
• 173019-85-7 3-bromo-1-(4-methoxyphenyl)propyne 
• 62-53-3 aniline 
• 2881-83-6 ethyl 4-methoxybenzoylacetate 
• 103-71-9 phenyl isocyanate 
• 55991-69-0 5-(4-methoxyphenyl)-2,3-dihydro-2,3-furandione 
• 22027-50-5 methyl 3-(4-methoxybenzoyl)acetate 
• 87769-44-6 6-(4-methoxyphenyl)-2,2-dimethyl-4H-1,3-dioxin-4-one 
• 100-07-2 4-methoxy-benzoyl chloride 

Downstream Products

• 1387590-51-3 2-(4-methoxybenzoyl)-N-phenylacrylamide 
• 1387590-06-8 (R)-2-(4-methoxybenzoyl)-N-phenyloxirane-2-carboxamide 
• 1393463-29-0 2-(4-methoxybenzoyl)-N-phenyloxirane-2-carboxamide 
• 37118-72-2 2-hydroxy-4-(4-methoxyphenyl)quinoline 
• 37118-73-3 2-chloro-4-(4-methoxyphenyl)quinoline 
• 37118-72-2 4-(p-methoxyphenyl)-2-(1H)-quinolinone 
• 757951-26-1 (Z)-3-amino-3-(4-methoxyphenyl)-N-phenylacrylamide 

Relevant articles and documents

1,4,2-Dioxazol-5-ones as Isocyanate Equivalents: An Efficient Synthesis of 2-Quinolinones via β-Keto Amides

Under thermal conditions, 1,4,2-dioxazol-5-ones are known to undergo decarboxylation followed by Lossen's rearrangement to yield isocyanates. Described herein is the in situ trapping of the resulting isocyanates with carbon nucleophiles to synthesize β-keto amides. Furthermore, a general and mild method for the conversion of the resulting β-keto amides into quinolin-2-ones is reported.

Silver(I)-catalyzed tandem approach to β-oxo amides

A facile and efficient AgI-catalytic approach is reported for the first time to synthesize β-oxo amides from β-oxo esters a with broad substrate scope in good to excellent yields. Crossover and in situ NMR studies confirmed that the reaction occurred through a new pathway and not by the traditional condensation reaction. The key advantages of this method are the readily available starting materials, the air-stable reaction, the simple protocol, and the environmental friendliness. A new, catalytic approach to the synthesis of β-oxo amides from β-oxo esters with a broad substrate scope in good to excellent yields was developed. In situ NMR spectroscopy and crossover experiments confirmed the reaction mechanism.

Highly enantioselective epoxidation catalyzed by cinchona thioureas: Synthesis of functionalized terminal epoxides bearing a quaternary stereogenic center

A brilliant debut! Cinchona thioureas have been reported for the first time as catalysts in the area of asymmetric oxidations. They efficiently promote an unprecedented highly enantioselective epoxidation of deactivated 1,1-disubstituted alkenes to terminal epoxides containing a quaternary stereogenic center (see scheme). Copyright