98215-46-4Relevant articles and documents
A highly enantioselective access to tetrahydroisoquinoline and β-carboline alkaloids with simple noyori-type catalysts in aqueous media
Evanno, Laurent,Ormala, Joel,Pihko, Petri M.
supporting information; experimental part, p. 12963 - 12967 (2010/06/16)
Silver enhancement: A very convenient modified protocol for the enantioselective transfer hydrogenation of dihydroisoquinoline skeletons under aqueous conditions is reported. Unmodified Noyori ligands can be used and the activity of the catalyst is greatly enhanced with silver additives (see scheme). The protocol was used in a very short synthesis of the alkaloids (S)-harmicine and (S)-crispine.
Syntheses of 2-(3,4-dimethoxyphenyl)ethylamine derivatives and their antiulcer activities
Hosokami,Kuretani,Higashi,Asano,Ohya,Takasugi,Mafune,Miki
, p. 2712 - 2719 (2007/10/02)
A series of acyl derivatives of 2-(3,4-dimethoxyphenyl)ethylamine (4) were synthesized and evaluated for their effectiveness to prevent water-immersion stress-induced gastric ulceration when given intraperitoneally to rats. Among them N-[2-(3,4-dimethoxyp