98583-80-3

Basic information

• Product Name: Propanamide, 2-bromo-N,2-dimethyl-N-phenyl-
• CAS NO: 98583-80-3
• Molecular Formula: C11H14BrNO
• Molecular Weight: 256.142
• Mol File: 98583-80-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Propanamide, 2-bromo-N,2-dimethyl-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanamide, 2-bromo-N,2-dimethyl-N-phenyl-(98583-80-3)
• EPA Substance Registry System: Propanamide, 2-bromo-N,2-dimethyl-N-phenyl-(98583-80-3)

Safety Data

• Hazardous Substances Data: 98583-80-3(Hazardous Substances Data)

Upstream product

• 55577-65-6 2,N-dimethyl-N-phenylpropanamide 
• 15796-89-1 N-methyl-N-phenylmethacrylamide 
• 20769-85-1 2-bromoisobutyric acid bromide 
• 100-61-8 N-methylaniline 

Downstream Products

• 15796-89-1 N-methyl-N-phenylmethacrylamide 
• 108-95-2 phenol 
• 55577-65-6 2,N-dimethyl-N-phenylpropanamide 
• 20200-86-6 1,3,3-trimethyl-1,3-dihydro-2H-indol-2-one 
• 100134-55-2 2-cyano-N,2-dimethyl-N-phenylpropanamide 
• 647018-71-1 (1-{tert-butyl-[1-methyl-1-(methyl-phenyl-carbamoyl)-ethoxy]-amino}-2,2-dimethyl-propyl)-phosphonic acid diethyl ester 
• 31883-80-4 3,4-dihydro-1,3-dimethylquinolin-2(1H)-one 

Relevant articles and documents

Hydroarylation of Activated Alkenes Enabled by Proton-Coupled Electron Transfer

Hydroarylation of alkenes has been demonstrated to be an atom-economic approach to access functionalized arenes from easily accessible raw materials. Herein, we report a visible light-induced photocatalytic system that enables intramolecular hydroarylation of N-arylacrylamides with high 5-exo-trig selectivity through robust proton-coupled electron transfer (PCET). This mild hydroarylation protocol provides a straightforward entry to structurally valuable oxindoles and complements previously established 6-endo-trig cyclization by photochemical triplet energy transfer (TET).

Visible-Light-Driven Aryl Migration and Cyclization of α-Azido Amides

This paper reports two new visible-light-promoted radical reactions of α-azido amides. By catalysis of [Ir(ppy)2(dtbbpy)]PF6 with i-Pr2NEt as the reducing agent, N-aryl α-azido tertiary amides were first converted to the corresponding aminyl radicals through reduction of the azido group; the aminyl radicals then underwent N-to-N aryl migration to give α-anilinyl-functionalized amides. α-Azido secondary amides, on the other hand, reacted with the solvent ethanol and i-Pr2NEt to afford the imidazolinone products.

Alkoxyamine-Mediated Radical Synthesis of Indolinones and Indolines

(Equation presented) Thermolysis of α-alkoxyamino propionanilides produces indolinones, whereas thermal reaction of N-allylaniline derivatives with various Tordo-type alkoxyamines results in formation of indolines in the radical regime.