98966-17-7 Usage
Description
4,4'-dihydroxy-N,3'-biacetanilide is a chemical compound that is an impurity of Acetaminophen (A161220), an analgesic and antipyretic medication. It is characterized by the presence of two hydroxyl groups and an amide linkage between two aromatic rings.
Uses
Used in Pharmaceutical Research:
4,4'-dihydroxy-N,3'-biacetanilide is used as a reagent in pharmaceutical research for investigating mechanisms related to liver and kidney damage caused by acetaminophen. Its study can provide insights into the side effects and toxicity of the widely used pain reliever and fever reducer, potentially leading to the development of safer alternatives or treatment strategies for acetaminophen-induced organ damage.
Check Digit Verification of cas no
The CAS Registry Mumber 98966-17-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,9,6 and 6 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 98966-17:
(7*9)+(6*8)+(5*9)+(4*6)+(3*6)+(2*1)+(1*7)=207
207 % 10 = 7
So 98966-17-7 is a valid CAS Registry Number.
98966-17-7Relevant articles and documents
Photochemical Oxygenation of Phenols by Pyrimidopteridine N-Oxide. Comparative Studies with Pyridazine and Isoalloxazine N-Oxides
Sako, Magoichi,Ohara, Seiji,Hirota, Kosaku,Maki, Yoshifumi
, p. 3339 - 3344 (2007/10/02)
1,3,7,9-Tetrabutylpyrimidopteridine-2,4,6,8(1H,3H,7H,9H)-tetraone 5-oxide 1 transfers its N-oxide oxygen to phenols, i.e., phenol 5, p-cresol 6, L-tyrosine methyl ester 7, and p-hydroxyacetanilide (acetaminophen) 8, under photochemical conditions to give the corresponding dihydric phenols as major products without any accompanying photochemical intramolecular rearrangements of the N-oxide group taking place.This oxygenation is reasonably explained in terms of a photo-induced single electron transfer (SET) followed by oxygen-atom transfer (the SET mechanism) which occurs via the initial formation of a charge-transfer complex between compound 1 and the phenols employed.Comparative experiments with 3,10-dibutylisoalloxazine 5-oxide 3 and 3-methylpyridazine 2-oxide 4 well demonstrate the simplicity and the mechanistic characteristics of the photochemistry of compound 1.
