Role of phosphorylcholine (cas 107-73-3) in Streptococcus pneumoniae and nontypeable Haemophilus influenzae adherence to epithelial cells☆
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Add time:08/19/2019 Source:sciencedirect.com
Objectivephosphorylcholine (cas 107-73-3) (PC) is a structural component of Streptococcus pneumoniae (Spn) and nontypeable Haemophilus influenzae (NTHi), and is known to be associated with adherence through the platelet activating factor receptor (PAF-R). Furthermore, high PC expression is considered to be involved in Spn and NTHi virulence. In this study, we examined the influence of PC expression on the adherence of Spn and NTHi to epithelial cells in order to clarify the potential effectiveness of a vaccine targeting PC.
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