A concise first total synthesis of the antitumour antibiotic belactosin A is reported, involving coupling of beta-lactone carboxylic acid 3 with N-Ala-aminocyclopropyl alanine 11.
Armstrong, Alan,Scutt, James N
p. 510 - 511
(2007/10/03)
Absolute configuration of the four stereoisomers of valnoctamide (2- ethyl-3-methyl valeramide), a potentially new stereospecific antiepileptic and CNS drug
Valnoctamide (2-ethyl-3-methyl valeramide, Nirvanil, VCD), a mild tranquilizer endowed with anticonvulsant properties, exhibits diastereoselective and enantioselective pharmacokinetics in healthy subjects and epileptic patients. The purpose of this paper
Roeder, Michael,Spiegelstein, Ofer,Schurig, Volker,Bialer, Meir,Yagen, Boris
p. 841 - 853
(2007/10/03)
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