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27486-87-9

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27486-87-9 Usage

General Description

AC-CYS(TRT)-OH, also known as N-alpha-Acetyl-L-cysteine-O-trityl, is a derivative of L-cysteine, an amino acid. The acetyl group (AC) at one end of the molecule and a hydroxyl group (OH) at the other end increase its solubility and stability. The trityl group (TRT) is a protective group, which prevents unwanted reactions. This chemical is primarily used in peptide synthesis, where protecting groups like TRT are crucial for directing the sequence of amino acids. The modification with AC and TRT allows this compound to participate in chemical reactions without altering the cysteine amino acid itself, thus enabling the creation of specific peptide sequences.

Check Digit Verification of cas no

The CAS Registry Mumber 27486-87-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,4,8 and 6 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 27486-87:
(7*2)+(6*7)+(5*4)+(4*8)+(3*6)+(2*8)+(1*7)=149
149 % 10 = 9
So 27486-87-9 is a valid CAS Registry Number.

27486-87-9 Well-known Company Product Price

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  • Alfa Aesar

  • (H66689)  N-Acetyl-S-trityl-L-cysteine, 95%   

  • 27486-87-9

  • 250mg

  • 294.0CNY

  • Detail
  • Alfa Aesar

  • (H66689)  N-Acetyl-S-trityl-L-cysteine, 95%   

  • 27486-87-9

  • 1g

  • 784.0CNY

  • Detail
  • Alfa Aesar

  • (H66689)  N-Acetyl-S-trityl-L-cysteine, 95%   

  • 27486-87-9

  • 5g

  • 2940.0CNY

  • Detail

27486-87-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name AC-CYS(TRT)-OH

1.2 Other means of identification

Product number -
Other names AC-CYSTEINE(TRT)-OH

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:27486-87-9 SDS

27486-87-9Relevant articles and documents

Maleimidation of dextran and the application in designing a dextran-camptothecin conjugate

Zhu, Qiwen,Bao, Bin,Zhang, Qiumeng,Yu, Jiahui,Lu, Wei

, p. 2818 - 2823 (2018)

Camptothecin analogs, as commonly used chemotherapy drugs, usually have poor water solubility which has limited their use in the clinic. In order to improve the water-solubility of camptothecin, a new dextran derivative Dex-Mal was synthesized and used in

PROTECTED FUMARIC ACID-BASED METABOLITES FOR THE TREATMENT OF AUTOIMMUNE DISEASES

-

Page/Page column 34; 35; 36, (2017/08/01)

The present invention provides novel cell-permeable fumarate acyl mercaptoethylamines (FAMs) which have cellular effects including induction of Nrf2 and inhibition of the NFkB pathway. These compounds have utility in medicine including their use in treatment of diseases such as Multiple sclerosis, Non-alcoholic Steatohepatitis, Psoriasis, Inflammatory Arthritis, Inflammatory Bowel Disease, Asthma, Chronic Obstructive Pulmonary Disease, Cancer, Parkinson's Disease, Alzheimer's Disease, Huntington's Disease and Amyotrophic Lateral Sclerosis.

Substrate-initiated synthesis of cell-penetrating poly(disulfide)s

Bang, Eun-Kyoung,Gasparini, Giulio,Molinard, Guillaume,Roux, Aurélien,Sakai, Naomi,Matile, Stefan

supporting information, p. 2088 - 2091 (2013/04/10)

Lessons from surface-initiated polymerization are applied to grow cell-penetrating poly(disulfide)s directly on substrates of free choice. Reductive depolymerization after cellular uptake should then release the native substrates and minimize toxicity. In the presence of thiolated substrates, propagators containing a strained disulfide from asparagusic or, preferably, lipoic acid and a guanidinium cation polymerize into poly(disulfide)s in less than 5 min at room temperature at pH 7. Substrate-initiated polymerization of cationic poly(disulfide)s and their depolymerization with dithiothreitol causes the appearance and disappearance of transport activity in fluorogenic vesicles. The same process is further characterized by gel-permeation chromatography and fluorescence resonance energy transfer.

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