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M. M. MAJD ET AL.
CH3), 1.10 (t, J = 7.1 Hz, 3H, CH3). 13C NMR (DMSO-d6) δ = 166.20, 152.99, 149.22,
145.73, 129.25, 128.12, 127.11, 100.13, 60.04, 54.83, 18.64, 14.94.
4-(4-Chlorophenyl)-5-(ethoxycarbonyl)-6-methyl-3,4-dihydropyrimidin-
1
2(1H)-one (4b). H NMR (DMSO-d6): δ = 9.24 (s, 1H, NH), 7.77 (s, 1H, NH), 7.40
(d, 8.4 Hz, 2H, arom CH), 7.25 (d, J = 8.4 Hz, 2H, arom CH), 5.14 (d, J = 3.3 Hz, 1H,
CH), 3.99 (q, J = 7.1 Hz, 2H, CH2), 2.26 (s, 3H, CH3), 1.10 (t, J = 7.1 Hz, 3H, CH3).
13C NMR (DMSO-d6) δ = 166.07, 152.79, 149.60, 144.66, 132.64, 129.26, 129.05, 99.69,
60.12, 54.28, 18.67, 14.94.
5-(Ethoxycarbonyl)-4-(4-methoxyphenyl)-6-methyl-3,4-dihydropyrimidin-
1
2(1H)-one (4e). H NMR (DMSO-d6): δ = 9.15 (s, 1H, NH), 7.67 (s, 1H, NH), 7.15
(d, J = 8.6 Hz, 2H, arom CH), 6.88 (d, J = 8.6 Hz, 2H, arom CH), 5.10 (d, J = 2.9 Hz,
1H, CH), 3.99 (q, J = 7.1 Hz, 2H, CH2), 3.72 (s, 3H, CH3), 2.24 (s, 3H, CH3), 1.11
(t, J = 7.1 Hz, 3H, CH3). 13C NMR (DMSO-d6) δ = 166.24, 159.31, 153.02, 148.87,
137.92, 128.26, 114.56, 100.44, 60.01, 55.91, 54.20, 18.62, 14.96.
5-(Ethoxycarbonyl))-6-methyl-4-phenyl-3,4-dihydropyrimidine-2(1H)-thi
1
one (4f). H NMR (DMSO-d6): δ = 10.33 (s, 1H, NH), 9.65 (s, 1H, NH), 7.37–7.22
(m, 5H, arom CH), 5.18 (d, J = 3.4 Hz, 1H, CH), 4.02 (q, J = 7.1 Hz, 2H, CH2), 2.30
(s, 3H, CH3), 1.12 (t, J = 7.1 Hz, 3H, CH3). 13C NMR (DMSO-d6) δ = 175.11, 165.99,
145.89, 144.37, 129.43, 128.54, 127.25, 101.58, 60.45, 54.91, 18.03, 14.87.
5-(Ethoxycarbonyl)-4-(4-methylphenyl)-6-methyl-3,4-dihydropyrimidine-
1
2(1H)-thione (4i). H NMR (DMSO-d6): δ = 10.30 (s, 1H, NH), 9.61 (s, 1H, NH),
7.15 (d, J = 8.0 Hz, 2H, arom CH), 7.11 (d, J = 8.0 Hz, 2H, arom CH), 5.14 (d, J =
3.0 Hz, 1H, CH), 4.01 (q, J = 7.1 Hz, 2H, CH2), 2.30 (s, 3H, CH3), 2.27 (s, 3H, CH3), 1.11
(t, J = 7.1 Hz, 3H, CH3). 13C NMR (DMSO-d6) δ = 175.03, 166.01, 145.73, 141.47,
137.76, 129.92, 127.16, 101.70, 60.42, 54.61, 21.53, 18.01, 14.89.
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