beta-hydroxyleucine

Base Information Edit

Chemical Name:beta-hydroxyleucine
CAS No.:5817-22-1
Molecular Formula:C₆H₁₃NO₃
Molecular Weight:147.174
Hs Code.:
Mol file:5817-22-1.mol

Synonyms:L-Leucine, 3-hydroxy-;(2S)-2-Amino-3-hydroxy-4-methylpentanoic acid;β-Hydroxyleucine;AC1L34WJ;AC1Q5QJ4;

Suppliers and Price of beta-hydroxyleucine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
(2S,3S)-(2S,3R)-2-Amino-3-hydroxy-4-methylpentanoicAcidHClSalt
5 mg
$ 3000.00

Biosynth Carbosynth
(2S,3S)-(2S,3R)-2-Amino-3-hydroxy-4-methylpentanoic acid hydrochloride salt
250 mg
$ 305.00

Biosynth Carbosynth
(2S,3S)-(2S,3R)-2-Amino-3-hydroxy-4-methylpentanoic acid hydrochloride salt
100 mg
$ 160.00

Biosynth Carbosynth
(2S,3S)-(2S,3R)-2-Amino-3-hydroxy-4-methylpentanoic acid hydrochloride salt
50 mg
$ 104.00

Biosynth Carbosynth
(2S,3S)-(2S,3R)-2-Amino-3-hydroxy-4-methylpentanoic acid hydrochloride salt
1 g
$ 895.00

Biosynth Carbosynth
(2S,3S)-(2S,3R)-2-Amino-3-hydroxy-4-methylpentanoic acid hydrochloride salt
500 mg
$ 480.00

AK Scientific
beta-Hydroxyleucine
100mg
$ 320.00

Total 6 raw suppliers

Chemical Property of beta-hydroxyleucine Edit

Chemical Property:

Vapor Pressure:2.87E-05mmHg at 25°C
Refractive Index:1.495
Boiling Point:319 °C at 760 mmHg
Flash Point:146.7 °C
PSA：83.55000
Density:1.181 g/cm³
LogP:0.11550
Storage Temp.:-20°C Freezer, Under Inert Atmosphere
Solubility.:Methanol, Water

Purity/Quality:

99% ^*data from raw suppliers

(2S,3S)-(2S,3R)-2-Amino-3-hydroxy-4-methylpentanoicAcidHClSalt ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of beta-hydroxyleucine

There total 51 articles about beta-hydroxyleucine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: C₃₁H₃₃N₃NiO₄

: 5817-22-1,6645-45-0,10148-70-6,28908-11-4,35016-54-7,35016-62-7,87421-23-6,87421-24-7,10148-71-7
(2S,3R)-3-hydroxyleucine

Guidance literature:: With hydrogenchloride; In methanol; for 1h; Inert atmosphere; Reflux;
DOI:10.1021/ol503507g

Reference yield: 80.0%

: 78-84-2
isobutyraldehyde

: 5817-22-1,6645-45-0,10148-70-6,28908-11-4,35016-54-7,35016-62-7,87421-23-6,87421-24-7,10148-71-7
(2S,3R)-3-hydroxyleucine

: (S)-2-N-(N-benzyl-L-prolyl)aminobenzophenone hydrochloride

Guidance literature:: isobutyraldehyde; Ni(II)-(S)-o-[N-(N'-benzylprolyl)amino]benzophenone/glycine Schiff base complex; With sodium hydride; In tetrahydrofuran; at 16 ℃; for 0.166667h;

With hydrogenchloride; In methanol; Heating;
DOI:10.1016/S0957-4166(01)00071-4

Reference yield: 66.0%

: (2S,3R)-3-formyloxy-4-methyl-2-trifluoroacetamido pentan-1-oic acid

: 5817-22-1,6645-45-0,10148-70-6,28908-11-4,35016-54-7,35016-62-7,87421-23-6,87421-24-7,10148-71-7
(2S,3R)-3-hydroxyleucine

Guidance literature:: With potassium hydroxide; Dowex H⁺; 1.) 100 deg C, 5 h; 2.) r.t., (pH=4) then 80 deg C, 5 min;
DOI:10.1016/0040-4020(95)00024-3