Technology Process of N-(4-Chlorophenyl)propanamide
There total 14 articles about N-(4-Chlorophenyl)propanamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
propionic acid;
With
iodine; triethylamine; phosphorous acid trimethyl ester;
In
dichloromethane;
for 0.166667h;
Cooling with ice;
Inert atmosphere;
4-chloro-aniline;
In
dichloromethane;
at 20 ℃;
for 3h;
Inert atmosphere;
Cooling with ice;
DOI:10.1002/ejoc.201101030
- Guidance literature:
-
With
copper(l) iodide; cesium fluoride; N,N`-dimethylethylenediamine;
In
tetrahydrofuran;
at 25 ℃;
for 18 - 24h;
Inert atmosphere;
DOI:10.1016/j.tetlet.2009.10.041
- Guidance literature:
-
With
sulfuric acid;
at 100 ℃;
for 4h;
Temperature;
Reagent/catalyst;
