Menthyl acetate

Base Information

• Chemical Name: Menthyl acetate
• CAS No.: 29066-34-0
• Molecular Formula: C₁₂H₂₂O₂
• Molecular Weight: 198.305
• Hs Code.: 2915390090
• Mol file: 29066-34-0.mol

Synonyms:[(1S,2R,5S)-5-Methyl-2-propan-2-ylcyclohexyl] acetate;

Chemical Property of Menthyl acetate

Chemical Property:

• Appearance/Colour: COA
• Vapor Pressure: 0.0707mmHg at 25°C
• Refractive Index: 1.448
• Boiling Point: 228-229oC
• Flash Point: 92.2°C
• PSA: 26.30000
• Density: 0.922
• LogP: 3.01030

Purity/Quality:

99%, ^*data from raw suppliers

Menthyl acetate primary reference standard ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Menthyl acetate

There total 46 articles about Menthyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

menthol (89-78-1) + acetic anhydride (108-24-7) → 2-isopropyl-5-methylcyclohexyl acetate (89-48-5,2230-87-7,2552-91-2,2623-23-6,5157-89-1,16409-45-3,20777-36-0,20777-45-1,29066-34-0,42241-42-9,50539-17-8,55058-46-3,79199-84-1,146502-80-9)

Guidance literature:

With lithium perchlorate; at 25 ℃; for 22h;

DOI:10.1055/s-2001-17483

Reference yield: 97.0%

Isopropenyl acetate (108-22-5) + menthol (89-78-1) → 2-isopropyl-5-methylcyclohexyl acetate (89-48-5,2230-87-7,2552-91-2,2623-23-6,5157-89-1,16409-45-3,20777-36-0,20777-45-1,29066-34-0,42241-42-9,50539-17-8,55058-46-3,79199-84-1,146502-80-9)

Guidance literature:

With P(MeNCH₂CH₂)3N; In tetrahydrofuran; at 50 ℃; for 14h;

DOI:10.1021/jo981819m

Reference yield: 95.0%

menthol (89-78-1) + acetyl chloride (75-36-5) → 2-isopropyl-5-methylcyclohexyl acetate (89-48-5,2230-87-7,2552-91-2,2623-23-6,5157-89-1,16409-45-3,20777-36-0,20777-45-1,29066-34-0,42241-42-9,50539-17-8,55058-46-3,79199-84-1,146502-80-9)

Guidance literature:

With potassium fluoride on basic alumina; In toluene; for 2h;

DOI:10.1016/S0040-4020(01)00677-9

upstream raw materials:

acetic anhydride

menthol

[1-α]-5-methyl-2-[1-methylethyl]-cyclohexanol

vinyl acetate

Downstream raw materials:

3-iodo-p-menthane

3ξ-bromo-1r-methyl-4t-isopropyl-cyclohexane

(1S,2R,5S)-(+)-menthol

(-)-menthol

Refernces

• 1、 -. "A Method For Preparing (Meth)Acrylic Acid Ester Based Compound". Paragraph 0071-0072. . Retrieved 2021/05/07.
• 2、 Belkacemi, Fatima Zohra,Merabet-Khelassi, Mounia,Aribi-Zouioueche, Louisa,Riant, Olivier. "Production of l-menthyl acetate through kinetic resolution by?Candida cylindracea lipase: effects of alkaloids as additives". . p. 6847 - 6860. Retrieved 2018/07/15.