N,N-phthaloyl-taurine

Base Information

• Chemical Name: N,N-phthaloyl-taurine
• CAS No.: 4443-24-7
• Molecular Formula: C10H9NO5S
• Molecular Weight: 255.251
• Mol file: 4443-24-7.mol

Synonyms:2H-Isoindole-2-ethanesulfonic acid, 1,3-dihydro-1,3-dioxo-

Chemical Property of N,N-phthaloyl-taurine

Chemical Property:

• PSA: 100.13000
• Density: 1.608g/cm³
• LogP: 1.18910
• Storage Temp.: 2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

2-(1,3-Dioxoisoindolin-2-yl)ethanesulfonicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N-phthaloyl-taurine

There total 1 articles about N,N-phthaloyl-taurine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

phthalic anhydride (85-44-9) + Tau (107-35-7) → NCS 731 (4443-24-7)

Guidance literature:

With potassium acetate; acetic acid;

DOI:10.1016/S0960-894X(98)00270-4

Reference yield:

NCS 731 (4443-24-7) → 2-phthalimidoethane sulfonamide (4443-23-6,86660-00-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / PCl₅ / benzene

2: 70 percent / NH₃ / tetrahydrofuran / 0 °C

With phosphorus pentachloride; ammonia; In tetrahydrofuran; benzene;

DOI:10.1016/S0960-894X(98)00270-4

Reference yield:

NCS 731 (4443-24-7) → 2-(1,3-dioxoisoindolin-2-yl)-N-methylethanesulfonamide (81428-01-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / PCl₅ / benzene

2: tetrahydrofuran / 0 °C

With phosphorus pentachloride; In tetrahydrofuran; benzene;

DOI:10.1016/S0960-894X(98)00270-4

upstream raw materials:

phthalic anhydride

Tau

Downstream raw materials:

2-phthalimidoethane sulfonamide

2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)ethanesulfonic acid dimethylamide

2-(1,3-dioxoisoindolin-2-yl)-N-methylethanesulfonamide

Refernces