(+)-ETHYL D-LACTATE

Base Information

• Chemical Name: (+)-ETHYL D-LACTATE
• CAS No.: 7699-00-5
• Molecular Formula: C5H10O3
• Molecular Weight: 118.133
• Hs Code.: 2918110000
• Mol file: 7699-00-5.mol

Synonyms:Lacticacid, ethyl ester, D- (8CI);Propanoic acid, 2-hydroxy-, ethyl ester, (R)-;(+)-Ethyl 2-hydroxypropanoate;(+)-Ethyl 2-hydroxypropionate;(+)-Ethyllactate;(2R)-2-Hydroxypropanoic acid ethyl ester;(R)-(+)-Ethyl lactate;(R)-(+)-Lactic acid ethyl ester;(R)-2-Hydroxypropionic acid ethyl ester;(R)-Ethyl lactate;(R)-Lactic acid ethyl ester;D-Ethyl lactate;Ethyl(R)-2-hydroxypropanoate;Ethyl (R)-2-hydroxypropionate;Ethyl D-lactate;

Chemical Property of (+)-ETHYL D-LACTATE

Chemical Property:

• Refractive Index: n20/D 1.413
• Boiling Point: 154.5 °C at 760 mmHg
• PKA: 13.21±0.20(Predicted)
• Flash Point: 54.6 °C
• PSA: 46.53000
• Density: 1.05 g/cm³
• LogP: -0.06970
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

EthylD-Lactate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 10-37-41
• Safety Statements: 24-26-39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (+)-ETHYL D-LACTATE

There total 38 articles about (+)-ETHYL D-LACTATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

ethanol (64-17-5) + D-Lactic acid (10326-41-7,106989-11-1,26811-96-1,31587-11-8,26100-51-6) → (R)-Ethyl lactate (7699-00-5)

Guidance literature:

With salicylaldehyde; at 80 ℃; for 28h; chemoselective reaction; Inert atmosphere;

DOI:10.1039/c2ra23068b

Reference yield: 84.0%

ethanol (64-17-5) + (3R,5S,6R,9S)-3,9-Dimethyl-6-(1-methyl-1-phenyl-ethyl)-1,4-dioxa-spiro[4.5]decan-2-one (104196-77-2,104264-83-7) → (R)-Ethyl lactate (7699-00-5) + (-)-(2S,5R)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexanon (97371-54-5)

Guidance literature:

With hydrogenchloride; for 2h; Heating;

DOI:10.1021/jo00369a049

Reference yield: 76.0%

ethanol (64-17-5) + D-lactide (13076-17-0,26680-10-4,26969-66-4,615-95-2) → (R)-Ethyl lactate (7699-00-5)

Guidance literature:

With hydrogenchloride; In toluene;

DOI:10.1021/ja970018i

upstream raw materials:

ethanol

D-Lactic acid

2-oxo-propionic acid ethyl ester

2-nitryloxy-propionic acid ethyl ester

Downstream raw materials:

(L) Ethyl 2-chloropropanoate

2-phenylacetoxy-propionic acid ethyl ester

2-hydroxy-3-heptanone

(+)-2-Chlor-propionsaeure-aethylester

Refernces

• 1、 Guan, Zaihong,Lu, Shengmei,Li, Can. "Highly oxidized Pt species stabilized inside carbon nanotubes for asymmetric hydrogenation". . p. 1535 - 1542. Retrieved 2015.
• 2、 Baiker,Wandeler,Kuenzle,Schneider,Mallat. "Continuous Enantioselective hydrogenation of ethyl pyruvate in "Supercritical" ethan: Relation between phase behavior and catalytic performance". . p. 377 - 388. Retrieved 2001.
• 3、 Yang, Zeyu,Fu, Hengwei,Ye, Wenjie,Xie, Youyu,Liu, Qinghai,Wang, Hualei,Wei, Dongzhi. "Efficient asymmetric synthesis of chiral alcohols using high 2-propanol tolerance alcohol dehydrogenase: Sm ADH2 via an environmentally friendly TBCR system". . p. 70 - 78. Retrieved 2020/01/21.
• 4、 Chen, Rong,Liu, Qinghai,Wang, Hualei,Wei, Dongzhi,Xie, Youyu,Yang, Zeyu,Ye, Wenjie. "Efficient Asymmetric Synthesis of Ethyl (S)-4-Chloro-3-hydroxybutyrate Using Alcohol Dehydrogenase SmADH31 with High Tolerance of Substrate and Product in a Monophasic Aqueous System". . p. 1068 - 1076. Retrieved 2020/07/06.