pregnanediol 20-monoacetate

Base Information

• Chemical Name: pregnanediol 20-monoacetate
• CAS No.: 77790-40-0
• Molecular Formula: C₂₃H₃₈O₃
• Molecular Weight: 362.553
• Mol file: 77790-40-0.mol

Synonyms:pregnanediol 20-monoacetate

Chemical Property of pregnanediol 20-monoacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of pregnanediol 20-monoacetate

There total 1 articles about pregnanediol 20-monoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pregnanediol (80-92-2) + acetic acid (64-19-7,77671-22-8) → (20S)-20-hydroxy-5β-pregnan-3α-yl acetate (6100-25-0) + pregnanediol 20-monoacetate (77790-40-0) + 3α,20αF-diacetoxy-5β-pregnane (1174-69-2)

Guidance literature:

DOI:10.1080/00221320209598688

Reference yield:

20αF-acetoxy-5α-pregnan-3α-ol (6003-19-6,6158-05-0,36027-69-7,77790-40-0,95719-99-6,118490-26-9) → 20α-hydroxy-5α-pregnan-3-one (516-59-6)

Guidance literature:

Multi-step reaction with 2 steps

1: CrO₃; acetic acid

2: aq.-ethanolic NaOH

With chromium(VI) oxide; sodium hydroxide; acetic acid;

Reference yield:

pregnanediol 20-monoacetate (77790-40-0) → 20α-Hydroxy-5β-pregnan-3-one (54353-11-6)

Guidance literature:

Multi-step reaction with 2 steps

1: CrO₃; acetic acid

2: ethanolic KOH

With chromium(VI) oxide; potassium hydroxide; acetic acid;

DOI:10.1134/1.171130

upstream raw materials:

pregnanediol

acetic acid

Downstream raw materials:

3α-tosyloxy-5β-pregnan-20α-yl acetate

20α-Hydroxy-5β-pregnan-3-one

20α-hydroxy-5α-pregnan-3-one