Ethyl vincaminate

Base Information Edit

Chemical Name:Ethyl vincaminate
CAS No.:40163-56-2
Molecular Formula:C22H28 N2 O3
Molecular Weight:368.476
Hs Code.:2939800000
UNII:G6583YDK1Y
DSSTox Substance ID:DTXSID90960604
Nikkaji Number:J573.465G
Wikidata:Q27278822
Mol file:40163-56-2.mol

Synonyms:Ethyl vincaminate;40163-56-2;Ethylvincaminate;(+)-Vincaminic acid ethyl ester;Ethyl (+)-cis-vincaminate;UNII-G6583YDK1Y;G6583YDK1Y;Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, ethyl ester, (3a,14b,16a)-;Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, ethyl ester, (3-alpha,14-beta,16-alpha)-;ethyl (15S,17S,19S)-15-ethyl-17-hydroxy-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraene-17-carboxylate;Ethyl (12S,13aS,13bS)-13a-Ethyl-12-hydroxy-2,3,5,6,12,13,13a,13b-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate (Ethyl Vincaminate);Ethyl (12S,13aS,13bS)-13a-Ethyl-12-hydroxy-2,3,5,6,12,13,13a,13b-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]-naphthyridine-12-carboxylate;Vinpocetine impurity A;(+)-ETHYL VINCAMINATE;DTXSID90960604;VINCAMINIC ACID ETHYL ESTER;AKOS015843287;(+)-cis-Vincaminic Acid Ethyl-d5 Ester;LS-63699;(+)-CIS-VINCAMINIC ACID ETHYL ESTER;VINPOCETINE IMPURITY A [EP IMPURITY];Q27278822;Ethyl 14-hydroxy-14,15-dihydroeburnamenine-14-carboxylate;EBURNAMENINE-14-CARBOXYLIC ACID, 14,15-DIHYDRO-14-HYDROXY-, ETHYL ESTER, (3.ALPHA.,14.BETA.,16.ALPHA.)-

Suppliers and Price of Ethyl vincaminate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(+)-cis-VincaminicAcidEthylEster
10mg
$ 865.00

TRC
(+)-cis-VincaminicAcidEthylEster
5mg
$ 500.00

TRC
(+)-cis-VincaminicAcidEthylEster
1mg
$ 130.00

Sigma-Aldrich
Vinpocetine Related Compound A United States Pharmacopeia (USP) Reference Standard
30mg
$ 1230.00

American Custom Chemicals Corporation
EBURNAMENINE-14-CARBOXYLIC ACID, 14,15-DIHYDRO-14-HYDROXY-, ETHYL ESTER, (3A,14B,16A)- 95.00%
5MG
$ 499.93

Total 7 raw suppliers

Chemical Property of Ethyl vincaminate Edit

Chemical Property:

Vapor Pressure:1.33E-11mmHg at 25°C
Boiling Point:519.1°C at 760 mmHg
PKA:12.27±0.40(Predicted)
Flash Point:267.8°C
PSA：54.70000
Density:1.33g/cm³
LogP:3.28050
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:368.20999276
Heavy Atom Count:27
Complexity:612

Purity/Quality:

NLT 98% ^*data from raw suppliers

(+)-cis-VincaminicAcidEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2)(C(=O)OCC)O
Isomeric SMILES:CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4[C@](C2)(C(=O)OCC)O
Uses (+)-cis-Vincaminic Acid Ethyl Ester (Vinpocetine USP Related Compound A), is a derivative of Vinpocetine (D448350). It has been shown that under stressed conditions, vinpocetine equilibrates with Vincaminic Acid Ethyl Ester and hydrolyzes to Apovincaminic Acid (A729250).

Technology Process of Ethyl vincaminate

There total 24 articles about Ethyl vincaminate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%