10334-26-6Relevant articles and documents
Synthesis of 1,11,11-trimethyl-3,6-diazotricyclo [6.2.1.0 2,7]undeca-2,6-diene and 1,15,15-trimethyl-3,10-diazotetracyclo[10.2. 1.02,11.04,9]pentadeca-2,4(9),5,7,10-pentaene from camphoroquinone enantiomers
Adamenko,Frolova,Panteleeva,Kuchin
, p. 59 - 62 (2007)
Optically active camphordihydro-2,3-pyrazine and camphorquinoxaline were prepared from camphoroquinone enantiomers. It was shown that (1S,4R)-(+)-camphoroquinone was formed by oxidation of (1S,3R, 4R)-(-)-3-bromocamphor and (1R,4S)-(-)-camphoroquinone from (1R,3S, 4S)-(+)-3-bromocamphor, respectively. Camphor anhydride was a side product (6-10%) of the reaction. Springer Science+Business Media, Inc. 2007.
An improved synthesis of camphorquinone-3-oxime
Love, Brian E.,Jones, Edward G.
, p. 2831 - 2840 (1999)
Camphorquinone 3-oxime is prepared in 77% yield in one step from camphor. The synthesis avoids the use of toxic selenium reagents, and provides the syn compound as the major stereoisomer.
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Wulfman,D.S. et al.
, p. 522 - 529 (1975)
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The Role of Side-Arms for Supramolecular Affinity Materials Based on 9,9′-Spirobifluorenes
Pyka, Isabella,Nikl, Joachim,Schollmeyer, Dieter,Waldvogel, Siegfried R.
, p. 3501 - 3504 (2017)
An eightfold functionalized D2d-symmetric 9,9′-spirobifluorene was condensed with a collection of diketones with elaborated structural features to form three-dimensional supramolecular architectures with active surfaces. Gas-sorption measuremen
Synthesis and evaluation of camphor and cytisine-based cyanopyrrolidines as DPP-IV inhibitors for the treatment of type 2 diabetes mellitus
Kuranov,Tsypysheva,Khvostov,Zainullina, Liana F.,Borisevich,Vakhitova, Yu.V.,Luzina,Salakhutdinov
, p. 4402 - 4409 (2018)
In this study, bornyl- and cytisine-based cyanopyrrolidines as potent dipeptidyl peptidase-IV (DPP-IV) inhibitors were synthesised. The in vitro inhibiting activities of bornyl- and cytisine derivatives towards DPP-IV were evaluated. Bornyl-based cyanopyrrolidines were shown to have moderate inhibitory activity with regard to DPP-IV (1.27–15.78 μM). A docking study was performed to elucidate the structure-activity relationship of the obtained compounds. The in vivo hypoglycemic activities of the same compounds were evaluated with the oral glucose tolerance test (OGTT) in mice. Bornyl-based cyanopyrrolidines were shown to have good hypoglycemic activity.
An environment friendly preparation of 3-bromocamphor and camphorquinone
Kannappan, Jayaraman,Bedekar, Ashutosh V.
, p. 141 - 143 (2012)
The bromination of camphor has been carried out on a multi-gram scale by a mixture of KBr and KBrO3 in the presence of acid or with HBr/NaBr - H+ and H2O2/oxone as the oxidant. The 3-bromocamphor is then efficiently converted to camphorquinone by an improved oxidation protocol using DMSO and sodium carbonate of tetrabutyl ammonium iodide.
Stereoselective cyclopalladation of 2,3-camphorquinone 3-diphenylmethylimine
Gur'Eva,Zalevskaya,Alekseev,Frolova,Slepukhin,Kuchin
, p. 1543 - 1546 (2014)
A reaction of (1R,4 S)-3-diphenylmethylimino-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one with lithium tetrachloropalladate gives a palladium(II) complex with a monodentately coordinated ligand, whereas chiral palladacyclic compounds are formed in the case o
Charney,Tsai
, p. 7123,7126-7127, 7132 (1971)
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Mc Lauchlan et al.
, p. 1397,1400-1402 (1978)
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Rupe,Tommasi di Vignano
, p. 1078,1105 (1937)
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Method for producing camphorquinone by taking byproduct generated in camphor synthesis process as raw material
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Paragraph 0050; 0051, (2019/09/14)
The invention provides a method for producing camphorquinone by taking a byproduct generated in the camphor synthesis process as a raw material, belonging to the technical field of organic synthesis.The byproduct 3-camphene ester generated in the synthesis process of camphor is used as a starting material to prepare high-purity camphorquinone through refining, saponification, dehydrogenation, condensation, hydrolysis and recrystallization steps. The method has the beneficial effects that the value of the byproduct generated in the camphor synthesis process is used, industrial wastes are reduced, wastes are changed into valuables, environmental pressure is reduced, a brand-new path for the synthesis of the camphorquinone is provided, no heavy metals are used in all process steps, truly nontoxic chemical synthesis of the camphorquinone is realized, and the method is an economic and environment-friendly production process.