1035797-66-0Relevant articles and documents
Perfluoro alkoxylation reagent and preparation method and application thereof
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Paragraph 0142; 0143 0144; 0146; 0147; 0148, (2018/09/28)
The invention provides a perfluoro alkoxylation reagent and a preparation method and application thereof. Specifically, the provided perfluoro alkoxylation reagent shown as a formula A can be used fornormal perfluoro alkoxylation reactions in the field, especially trifluoromethylation. Raw materials related to the perfluoro alkoxylation reagent are low in price and easy to obtain, the reaction condition is mild, the operation is simple, the cost is low, and the reagent is easy to popularize and suitable for large-scale production. The formula A is as shown in the description.
A deeper insight into direct trifluoromethoxylation with trifluoromethyl triflate
Marrec, Olivier,Billard, Thierry,Vors, Jean-Pierre,Pazenok, Sergii,Langlois, Bernard R.
scheme or table, p. 200 - 207 (2010/04/30)
Commercially available fluorides (silver fluoride and n-tetrabutylammonium triphenyldifluorosilicate), combined with TFMT, allow a simple generation, in situ, of silver and n-tetrabutylammonium trifluoromethoxides which were able to react with electrophilic substrates. Silver trifluoromethoxide, which is usually more efficient than n-tetrabutylammonium trifluoromethoxide, converts, under mild conditions, primary aliphatic bromides and iodides, as well as primary and secondary benzylic or allylic bromides to the corresponding trifluoromethoxylated compounds. Several trifluoromethyl ethers, which could be valuable building-blocks, were prepared in such a way.