117069-75-7

Basic information

• Product Name: 3-AMINOINDOLIN-2-ONE
• Synonyms: CHEMBRDG-BB 4011261;AKOS BB-9966;3-AMINOINDOLIN-2-ONE;3-amino-1,3-dihydro-2H-indol-2-one(SALTDATA: HCl)
• CAS NO: 117069-75-7
• Molecular Formula: C₈H₈N₂O
• Molecular Weight: 148.16
• Mol File: 117069-75-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 323.7°Cat760mmHg
• Flash Point: 149.6°C
• Appearance: /
• Density: 1.248g/cm³
• Vapor Pressure: 0.000257mmHg at 25°C
• PKA: 14.05±0.40(Predicted)
• CAS DataBase Reference: 3-AMINOINDOLIN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINOINDOLIN-2-ONE(117069-75-7)
• EPA Substance Registry System: 3-AMINOINDOLIN-2-ONE(117069-75-7)

Safety Data

• Hazardous Substances Data: 117069-75-7(Hazardous Substances Data)

Usage

General Description

3-AMINOINDOLIN-2-ONE, also known as 3-Amino-2-oxindole, is a chemical compound with the molecular formula C8H8N2O. It is an indole derivative that contains an amino group at the 3-position and a ketone group at the 2-position. 3-AMINOINDOLIN-2-ONE is used in organic synthesis and pharmaceutical research, and it has been found to exhibit biological activities such as anticancer and antifungal properties. 3-AMINOINDOLIN-2-ONE has potential applications in the development of new drugs and agrochemicals due to its diverse pharmacological activities. Its unique structure and functional groups make it a valuable building block for the synthesis of novel compounds with therapeutic potential.

InChI:InChI=1/C8H8N2O/c9-7-5-3-1-2-4-6(5)10-8(7)11/h1-4,7H,9H2,(H,10,11)/p+1/t7-/m0/s1

Upstream product

• 607-28-3 (E)-1H-indole-2,3-dione 3-oxime 
• 91-56-5 indole-2,3-dione 
• 1165809-20-0 indole-2,3-dione 3-thiosemicarbazone 
• 612-53-3 (E)-3-iminoindolin-2-one 
• 67-56-1 methanol 
• 3265-35-8 indoline-2,3-dione-2-oxime 

Downstream Products

• 91-56-5 indole-2,3-dione 
• 476-34-6 isoindigo 

Relevant articles and documents

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Electrochemical characterization of isatin-thiosemicarbazone derivatives

Abstract: Herein, we have notably described the electrochemical behavior of four isatin-thiosemicarbazone derivatives. In this regard, cyclic voltammograms of isatin-3-thiosemicarbazone (ITSC), isatin-3-(N4-benzylthiosemicarbazone) (ITSC-Ph), 1-(5-nitro-2-oxoindolin-3-ylidene)thiosemicarbazide (NO2-ITSC) and 1-(5-nitro-2-oxoindolin-3-ylidene)-4-phenylthiosemicarbazide (NO2-ITSC-Ph) have demonstrated an irreversible oxidation process. More specifically, the generation of isatin and thiourea moieties as the final oxidation products was proposed. The cyclic voltammograms also demonstrate irreversible reduction processes of ITSC and ITSC-Ph in three steps. The proposed final products are 3-aminoindolin-2-one and thiourea moieties. In the cyclic voltammograms of NO2-ITSC and NO2-ITSC-Ph, five reduction processes were observed: three of them due to reduction of the nitro group. It was proposed that the formation of 5-hydroxyamino-3-iminoindolin-2-one and the thiourea moieties would be the final products. Graphic abstract: [Figure not available: see fulltext.] Electrochemical characterization of four isatin thiosemicarbazone derivatives is described. The compounds are irreversibly oxidized and reduced. Isatin moieties and thiourea are proposed to be the products generated after oxidation. Considering the reduction processes, the nitro group present at the isatin moiety is also reduced and influences the reduction products generated.