612-53-3

Basic information

• Product Name: 3-IMINO-2-INDOLINONE
• Synonyms: 3-IMINO-2-INDOLINONE;3-Imino-2-oxoindo-line;3-Iminoisatin;imesatin;Isatin-3-imide;3-iminooxindole;3-Iminoindolin-2-one;3-aminoindol-2-one
• CAS NO: 612-53-3
• Molecular Formula: C₈H₆N₂O
• Molecular Weight: 146.15
• Mol File: 612-53-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 343.7°C at 760 mmHg
• Flash Point: 161.6°C
• Appearance: /
• Density: 1.41g/cm³
• Vapor Pressure: 6.94E-05mmHg at 25°C
• Refractive Index: 1.707
• CAS DataBase Reference: 3-IMINO-2-INDOLINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-IMINO-2-INDOLINONE(612-53-3)
• EPA Substance Registry System: 3-IMINO-2-INDOLINONE(612-53-3)

Safety Data

• Hazardous Substances Data: 612-53-3(Hazardous Substances Data)

Usage

General Description

3-IMINO-2-INDOLINONE is a chemical compound with the molecular formula C9H6N2O. It is a heterocyclic compound with an indolinone backbone and a terminal imine group. 3-IMINO-2-INDOLINONE has been studied for its potential biological activities, including its role as a potential anti-cancer agent. It has also been explored for its potential use in organic synthesis and as a building block in the preparation of various pharmaceuticals and agrochemicals. The compound's unique structure and reactivity make it an intriguing target for further research and development in the field of medicinal chemistry and chemical synthesis.

InChI:InChI=1/C8H6N2O/c9-7-5-3-1-2-4-6(5)10-8(7)11/h1-4H,(H2,9,10,11)

Upstream product

• 28492-94-6 isatin-3-(N⁴-benzylthiosemicarbazone) 
• 1165809-20-0 indole-2,3-dione 3-thiosemicarbazone 

Downstream Products

• 91-56-5 indole-2,3-dione 
• 86-96-4 quinazoline-2,4-diol 
• 117069-75-7 3-aminoindolin-2-one 
• 1578230-19-9 (S)-methyl 2-(2,3-dioxoindolin-1-yl)-4-oxo-4-phenylbutanoate 
• 1261153-08-5 (E)-5-bromo-3-[[4-(methylsulfonyl)phenyl]methylene]indolin-2-one 
• 20870-79-5 5-nitrooxindole 
• 20870-78-4 5-bromo-2-indolin-2-one 

Relevant articles and documents

Electrochemical characterization of isatin-thiosemicarbazone derivatives

Abstract: Herein, we have notably described the electrochemical behavior of four isatin-thiosemicarbazone derivatives. In this regard, cyclic voltammograms of isatin-3-thiosemicarbazone (ITSC), isatin-3-(N4-benzylthiosemicarbazone) (ITSC-Ph), 1-(5-nitro-2-oxoindolin-3-ylidene)thiosemicarbazide (NO2-ITSC) and 1-(5-nitro-2-oxoindolin-3-ylidene)-4-phenylthiosemicarbazide (NO2-ITSC-Ph) have demonstrated an irreversible oxidation process. More specifically, the generation of isatin and thiourea moieties as the final oxidation products was proposed. The cyclic voltammograms also demonstrate irreversible reduction processes of ITSC and ITSC-Ph in three steps. The proposed final products are 3-aminoindolin-2-one and thiourea moieties. In the cyclic voltammograms of NO2-ITSC and NO2-ITSC-Ph, five reduction processes were observed: three of them due to reduction of the nitro group. It was proposed that the formation of 5-hydroxyamino-3-iminoindolin-2-one and the thiourea moieties would be the final products. Graphic abstract: [Figure not available: see fulltext.] Electrochemical characterization of four isatin thiosemicarbazone derivatives is described. The compounds are irreversibly oxidized and reduced. Isatin moieties and thiourea are proposed to be the products generated after oxidation. Considering the reduction processes, the nitro group present at the isatin moiety is also reduced and influences the reduction products generated.