1233731-18-4

Basic information

• Product Name: 5-(4-fluorophenyl)-1-phenyl-1H-tetrazole
• Synonyms: 5-(4-fluorophenyl)-1-phenyl-1H-tetrazole
• CAS NO: 1233731-18-4
• Molecular Weight: 240.24
• Mol File: 1233731-18-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-(4-fluorophenyl)-1-phenyl-1H-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-fluorophenyl)-1-phenyl-1H-tetrazole(1233731-18-4)
• EPA Substance Registry System: 5-(4-fluorophenyl)-1-phenyl-1H-tetrazole(1233731-18-4)

Safety Data

• Hazardous Substances Data: 1233731-18-4(Hazardous Substances Data)

Upstream product

• 366-63-2 4-fluoro-N-phenylbenzamide 
• 14210-25-4 5-Chloro-1-phenyltetrazole 
• 214360-58-4 2-(4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 133472-27-2 4-fluorophenylzinc chloride 

Relevant articles and documents

Transition-metal-free multinitrogenation of amides by C-C bond cleavage: A new approach to tetrazoles

A metal-free brand-new one-pot multinitrogenation of amides for the chemo- A nd regioselective synthesis of 1,5-disubstituted tetrazoles has been developed. By means of electrophilic amide activation, and further C-C bond cleavage and rearrangement, a diverse set of functionalized 1,5-DST derivatives were selectively constructed under mild conditions. As showcased in the mechanisms, the chemoselectivity is easily switched by the selection of the starting materials in the reaction.

Synthesis of 1,5-disubstituted tetrazoles via Suzuki-Miyaura cross-coupling of 5-chloro-1-phenyltetrazole

Suzuki-Miyaura coupling reactions of 5-chloro-1-phenyl-tetrazole with various functionalized arylboronic acids were investigated. In the presence of catalytic amounts of SPhos/Pd(OAc)2 or RuPhos/Pd(OAc)2, the reaction proceeded smoot