124436-59-5 Usage
Description
Pirodavir is a broad-spectrum antipicornaviral agent that exhibits activity against various serotypes of human rhinoviruses, coxsackievirus, poliovirus, and echovirus enteroviruses. It is known for its ability to modulate lipophilicity in human rhinovirus capsid binders, making it a valuable compound in the identification and development of potential antiviral agents.
Uses
Used in Antiviral Applications:
Pirodavir is used as an antiviral agent for modulating lipophilicity in human rhinovirus capsid binders, which aids in the identification and development of potential antiviral agents. Its broad-spectrum activity against different picornaviruses, including rhinoviruses, coxsackievirus, poliovirus, and echovirus, makes it a promising candidate for treating various viral infections.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, pirodavir is used as a compound for identifying potential antiviral agents. Its effectiveness against a wide range of picornaviruses makes it a valuable tool in the development of new antiviral drugs and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 124436-59-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,4,3 and 6 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 124436-59:
(8*1)+(7*2)+(6*4)+(5*4)+(4*3)+(3*6)+(2*5)+(1*9)=115
115 % 10 = 5
So 124436-59-5 is a valid CAS Registry Number.
InChI:InChI=1/C21H27N3O3/c1-3-26-21(25)18-5-7-19(8-6-18)27-15-12-17-10-13-24(14-11-17)20-9-4-16(2)22-23-20/h4-9,17H,3,10-15H2,1-2H3
124436-59-5Relevant articles and documents
An orally bioavailable oxime ether capsid binder with potent activity against human rhinovirus
Watson, Keith G.,Brown, Renee N.,Cameron, Rachel,Chalmers, David K.,Hamilton, Stephanie,Jin, Betty,Krippner, Guy Y.,Luttick, Angela,McConnell, Darryl B.,Reece, Phillip A.,Ryan, Jane,Stanislawski, Pauline C.,Tucker, Simon P.,Wu, Wen-Yang,Barnard, Dale L.,Sidwell, Robert W.
, p. 3181 - 3184 (2007/10/03)
A series of capsid-binding compounds was screened against human rhinovirus (HRV) using a CPE based assay. The ethyl oxime ether 14 was found to have outstanding anti-HRV activity (median IC50 4.75 ng/mL), and unlike the equivalent ethyl ester c
Novel pyridazinamine derivatives
-
, (2008/06/13)
Novel pyridazinamine derivatives having antiviral activity, compositions containing these compounds as active ingredient, and a method of destructing viruses or preventing the growth thereof in warm-blooded animals suffering from diseases caused by these viruses. Processes for preparing said compounds and compositions.
