124805-03-4

Basic information

• Product Name: ((E)-1-Chloro-2-methyl-3-phenyl-propenyl)-dimethyl-amine
• Synonyms: ((E)-1-Chloro-2-methyl-3-phenyl-propenyl)-dimethyl-amine
• CAS NO: 124805-03-4
• Molecular Weight: 209.719
• Mol File: 124805-03-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ((E)-1-Chloro-2-methyl-3-phenyl-propenyl)-dimethyl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: ((E)-1-Chloro-2-methyl-3-phenyl-propenyl)-dimethyl-amine(124805-03-4)
• EPA Substance Registry System: ((E)-1-Chloro-2-methyl-3-phenyl-propenyl)-dimethyl-amine(124805-03-4)

Safety Data

• Hazardous Substances Data: 124805-03-4(Hazardous Substances Data)

Upstream product

• 20929-40-2 2-methyl-N,N-dimethyl-3-phenylpropanamide 
• 1009-67-2 2-methyl-3-phenylpropanoic acid 
• 81136-08-5 2-methyl-3-phenylpropanoyl chloride 

Downstream Products

• 114234-22-9 N-<1-(N,N-Dimethylthiocarbamoyl)-1-methyl-2-phenylethyl>benzamid 
• 114234-23-0 4-benzyl-4-methyl-2-phenyl-1,3-thiazole-5(4H)-thione 
• 114234-21-8 2-benzyl-3-(dimethylamino)-2-methyl-2H-azirine 

Relevant articles and documents

Radical Cyclizations of Alkenyl-Substituted 4,5-Dihydro-1,3-thiazole-5-thiols

Heating of 5-alkenyl- or 5-alkinyl-4,5-dihydro-1,3-thiazole-5-thiols of type 5 in the presence of a radical initiator gave dithiaspirobicycles in fair-to-excellent yield (Scheme 3).Under analogous conditions, the 4,5-dihydro-4-vinyl-1,3-thiazole-5-thiol 5d underwent a cyclization to give the annellated dithiabicycle 7 (Scheme 4).In this reaction, a minor product 8 was formed by an unknown reaction mechanism.The structure of 8 was established by X-ray crystallography.The starting 1,3-thiazole-5-thiols 5 have been synthesized by carbophilic alkylation of the C=S group of 1,3-thiazole-5(4H)-thiones with Grignard-reagents or alkylcuprates.The thiazolethiones were obtained by the reaction of 3-amino-2H-azirines with thiobenzoic acid followed by sulfurization and cyclization.The 4-benzyl derivative 1b was thermally rearranged via 1,3-benzyl migration to yield the benzyl (1,3-thiazol-5-yl) sulfide 11 (Scheme 5).