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130107-96-9

130107-96-9

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130107-96-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 130107-96-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,1,0 and 7 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 130107-96:
(8*1)+(7*3)+(6*0)+(5*1)+(4*0)+(3*7)+(2*9)+(1*6)=79
79 % 10 = 9
So 130107-96-9 is a valid CAS Registry Number.

130107-96-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name dimethyl 4,4'-(propane-1,3-diylbis(oxy))bis(3-methoxybenzoate)

1.2 Other means of identification

Product number -
Other names 1,3-bis[2-methoxy-4-(methoxycarbonyl)phenoxy]propane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:130107-96-9 SDS

130107-96-9Relevant articles and documents

Macrocyclic pyrrolobenzodiazepine dimers as antibody-drug conjugate payloads

Donnell, Andrew F.,Zhang, Yong,Stang, Erik M.,Wei, Donna D.,Tebben, Andrew J.,Perez, Heidi L.,Schroeder, Gretchen M.,Pan, Chin,Rao, Chetana,Borzilleri, Robert M.,Vite, Gregory D.,Gangwar, Sanjeev

, p. 5267 - 5271 (2017)

Macrocyclic pyrrolobenzodiazepine dimers were designed and evaluated for use as antibody-drug conjugate payloads. Initial structure–activity exploration established that macrocyclization could increase the potency of PBD dimers compared with non-macrocyclic analogs. Further optimization overcame activity-limiting solubility issues, leading to compounds with highly potent (picomolar) activity against several cancer cell lines. High levels of in vitro potency and specificity were demonstrated with an anti-mesothelin conjugate.

PYRROLOBENZODIAZEPINE CONJUGATES

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Page/Page column 139; 140, (2018/04/27)

A compound of formula (I) : (I) and its conjugates.

PYRROLOBENZODIAZEPINE CONJUGATES

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Page/Page column 99, (2017/09/05)

A conjugate of formula (I), wherein L is a Ligand unit, D is a Drug Linker unit of formula (II), wherein either: (a) R10 and R11 form a nitrogen-carbon double bond between the nitrogen and carbon atoms to which they are bound; or (b)

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