1315477-55-4

Basic information

• Product Name: N-[2-(1-hydroxyprop-2-yn-1-yl)phenyl]-4-methylbenzenesulfonamide
• Synonyms: N-[2-(1-hydroxyprop-2-yn-1-yl)phenyl]-4-methylbenzenesulfonamide
• CAS NO: 1315477-55-4
• Molecular Weight: 301.366
• Mol File: 1315477-55-4.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: N-[2-(1-hydroxyprop-2-yn-1-yl)phenyl]-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(1-hydroxyprop-2-yn-1-yl)phenyl]-4-methylbenzenesulfonamide(1315477-55-4)
• EPA Substance Registry System: N-[2-(1-hydroxyprop-2-yn-1-yl)phenyl]-4-methylbenzenesulfonamide(1315477-55-4)

Safety Data

• Hazardous Substances Data: 1315477-55-4(Hazardous Substances Data)

Upstream product

• 6590-65-4 N-(2-Formyl-phenyl)-4-methyl-benzenesulfonamide 
• 74-86-2 acetylene 
• 6311-23-5 2-(toluene-4-sulfonylamino)-benzoic acid 
• 118-92-3 anthranilic acid 
• 90312-02-0 N-(2-hydroxymethylphenyl)-4-methylbenzenesulfonamide 
• 5344-90-1 2-Aminobenzyl alcohol 
• 78725-72-1 α-ethynyl-2-nitrophenylmethanol 
• 552-89-6 2-nitro-benzaldehyde 
• 1379771-04-6 C₉H₉NO 
• 98-59-9 p-toluenesulfonyl chloride 
• 529-23-7 o-aminobenzaldehyde 

Downstream Products

• 1315477-51-0 N-(2-(1-hydroxy-1-(thiophen-2-yl)prop-2-yn-1-yl)phenyl)-4-methylbenzenesulfonamide 
• 1315477-54-3 3-(2-(tosylamino)phenyl)pent-1-yn-3-ol 
• 1315477-72-5 3-(thiophen-2-yl)-1-tosyl-1H-indole-2-carbaldehyde 
• 1315477-77-0 3-ethyl-1-tosyl-1H-indole-2-carbaldehyde 
• 1315477-94-1 (E)-2-(iodomethylene)-1-tosylindolin-3-ol 
• 146384-54-5 1-(p-toluenesulfonyl)-1H-indole-2-carboxyaldehyde 
• 1357000-32-8 4-methyl-N-[2-(prop-2-yn-1-yl)phenyl]benzenesulfonamide 
• 1067892-79-8 1-tosyl-1,4-dihydroquinoline 
• 1448809-00-4 2-(iodomethylene)-1-tosylindolin-3-one 
• 1448808-99-8 2-(iodomethylene)-1-tosylindolin-3-one 
• 4630-20-0 3-Methyl-9H-carbazole 

Relevant articles and documents

Oxidative Cyclization of o-(1-Hydroxy-2-alkynyl)- N-tosylanilides for the Synthesis of 4-Quinolones

The treatment of easily accessible o-(1-hydroxy-2-alkynyl)-N-tosylanilides 1 with excess manganese(IV) oxide in the presence of substoichiometric tetrabutylammonium iodide (TBAI) in chloroform (or in the absence of TBAI in dimethylformamide, DMF) promoted a sequential oxidation/intramolecular hydroamination to give 4-quinolones 3 and/or (Z)-2-alkylidene-3-oxindoles (Z)-4 in good yields. Possibly, MnO2 played dual roles as an oxidant and as a Lewis acidic activator of intermediary ynones 2. The product distributions between 3 and (Z)-4 could be controlled by the choice of solvents.

Substituent-Guided Palladium-Ene Reaction for the Synthesis of Carbazoles and Cyclopenta[b]indoles

An efficient palladium-catalyzed intramolecular Trost-Oppolzer type Alder-ene strategy was developed for the synthesis of carbazoles and cyclopenta[b]indoles from easily accessible(3-allyl-1H-indol-2-yl)methyl acetates. This strategy was extended for the synthesis of naphthalenes and dibenzobenzofurans as well. In addition, a short synthesis of antibacterial and antifungal natural product glycozoline and its analogues was also achieved.

Synthesis of polysubstituted cyclopenta[b]indoles via relay gold(i)/Bronsted acid catalysis

An efficient relay catalytic process involving Au(i)/Bronsted acid to access various polysubstituted cyclopentannulated indoles from easily accessible 1-(2-aminophenyl)prop-2-ynols and readily available 1,3-dicarbonyls has been developed. In an unprecedented event, the intermediate 2-indolylmethyl cations undergo the cation-Ene reaction with various 1,3-dicarbonyls followed by an intramolecular Friedel-Crafts-type reaction generating functionalized cyclopenta[b]indoles. This journal is