13213-36-0

Basic information

• Product Name: PHENYLACETONE OXIME
• Synonyms: PHENYLACETONE OXIME;1-Phenylacetoneoxime;1-Phenylpropane-2-oneoxime
• CAS NO: 13213-36-0
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149.19
• Product Categories: Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes
• Mol File: 13213-36-0.mol
• Article Data: 33

Chemical Properties

• Boiling Point: 285.7°Cat760mmHg
• Flash Point: 169.2°C
• Appearance: /
• Density: 0.99g/cm³
• Vapor Pressure: 0.00129mmHg at 25°C
• Refractive Index: 1.514
• CAS DataBase Reference: PHENYLACETONE OXIME(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYLACETONE OXIME(13213-36-0)
• EPA Substance Registry System: PHENYLACETONE OXIME(13213-36-0)

Safety Data

• Hazardous Substances Data: 13213-36-0(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Synthetic Communications, 20, p. 2453, 1990 DOI: 10.1080/00397919008053193Tetrahedron, 48, p. 5317, 1992 DOI: 10.1016/S0040-4020(01)89028-1

InChI:InChI=1/C9H11NO/c1-8(10-11)7-9-5-3-2-4-6-9/h2-6,11H,7H2,1H3/b10-8+

Upstream product

• 58321-79-2 (Z)-(2-nitroprop-2-en-1-yl)benzene 
• 102-04-5 1,3-Diphenylpropanone 
• 17322-34-8 (2-nitropropyl)benzene 
• 103-79-7 1-phenyl-acetone 
• 2327-99-3 1-phenylpropadiene 
• 705-60-2 (2-nitroprop-1-enyl)benzene 
• 103-80-0 phenylacetyl chloride 
• 95092-10-7 N-methoxy-N-methyl-2-phenylacetamide 
• 673-32-5 1-Phenylprop-1-yne 
• 637-50-3 1-phenylpropene 
• 100-52-7 benzaldehyde 
• 60-15-1 2-amino-1-phenylpropane 
• 131981-75-4 (E)-1-bromo-4-(2-nitroprop-1-en-1-yl)benzene 
• 21892-60-4 1-(p-Bromphenyl)-2-nitro-1-propen 

Downstream Products

• 52271-37-1 N-Ethyl-N-(1-methyl-2-phenyl-ethyl)-hydroxylamine 
• 60-15-1 2-amino-1-phenylpropane 
• 63-90-1 N-hydroxy-1-phenyl-2-propylamine 
• 3121-50-4 (2-chloro-2-nitrosopropan-1-yl)benzene 
• 114971-31-2 1-phenylpropan-2-one O-acetyl oxime 
• 51650-27-2 1-benzyl-3-methylisoquinoline 
• 1517-68-6 (S)-1-phenylpropan-2-ol 
• 1572-95-8 (R)-1-phenyl-propan-2-ol 
• 76843-12-4 2-Ethyl-4-methyl-5-phenyloxazole 
• 18793-46-9 (Z)-N-(1-Methyl-2phenylethenyl)ethanamide 
• 18793-46-9 (E)-N-(1-Methyl-2-phenylethenyl)ethanamide 
• 18886-65-2 rac-3-methyl-2-phenyl-2H-azirine 
• 13901-69-4 dimethyl 2-methyl-5-phenyl-1H-pyrrole-3,4-dicarboxylate 

Relevant articles and documents

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ASPARAGINE DERIVATIVES AND METHODS OF USE THEREOF

The present invention relates to compounds of formulas (A) and (I), pharmaceutically acceptable salts thereof, and solvates of any of them, pharmaceutical compositions comprising them, methods of preparation thereof, intermediate compounds useful for the preparation thereof, and methods of treatment or prophylaxis of diseases, in particular cancer, such as colorectal cancer, using these. (A) (I)

Iridium-catalyzed highly chemoselective and efficient reduction of nitroalkenes to nitroalkanes in water

An iridium-catalyzed highly chemoselective and efficient transfer hydrogenation reduction of structurally diverse nitroalkenes was realized at very low catalyst loading (S/C = up to 10000 or 20?000), using formic acid or sodium formate as a traceless hydride donor in water. Excellent functionality tolerance is also observed. The turnover number and turnover frequency of the catalyst reach as high as 18?600 and 19?200 h-1, respectively. An inert atmosphere protection is not required. The reactivities of nitroalkenes are dependent on their substitution pattern, and the pH value is a key factor to accomplish the complete conversion and excellent chemoselectivity. Purification of products is achieved by simple extraction without column chromatography. The reduction procedure is facilely amplified to 10 g scale at 10?000 S/C ratio. The potential of this green reduction in enantioselective hydrogenation has been demonstrated.