1325725-67-4Relevant articles and documents
Enantioselective acylation of silyl ketene acetals through fluoride anion-binding catalysis
Birrell, James A.,Desrosiers, Jean-Nicolas,Jacobsen, Eric N.
supporting information; experimental part, p. 13872 - 13875 (2011/10/09)
A highly enantioselective acylation of silyl ketene acetals with acyl fluorides has been developed to generate useful α,α-disubstituted butyrolactone products. This transformation is promoted by a new thiourea catalyst and 4-pyrrolidinopyridine and represents the first example of enantioselective thiourea anion-binding catalysis with fluoride.