1355050-11-1

Basic information

• Product Name: (2S)-2-ethylbutyl 2-(((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
• Synonyms: (2S)-2-ethylbutyl 2-(((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
• CAS NO: 1355050-11-1
• Molecular Weight: 602.584
• Mol File: 1355050-11-1.mol
• Article Data: 8

Chemical Properties

• Density: 1.47±0.1 g/cm3(Predicted)
• CAS DataBase Reference: (2S)-2-ethylbutyl 2-(((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-2-ethylbutyl 2-(((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate(1355050-11-1)
• EPA Substance Registry System: (2S)-2-ethylbutyl 2-(((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate(1355050-11-1)

Safety Data

• Hazardous Substances Data: 1355050-11-1(Hazardous Substances Data)

Usage

Description

(2S)-2-ethylbutyl 2-((((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate is a complex organic compound with a unique molecular structure. It is characterized by its chiral centers and various functional groups, which contribute to its potential biological activities and applications.

Uses

Used in Pharmaceutical Industry:
(2S)-2-ethylbutyl 2-((((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate is used as a potential therapeutic agent for the treatment of viral infections, such as Ebola virus, due to its small molecule structure and demonstrated efficacy in preclinical studies.
Used in Antiviral Research:
In the field of antiviral research, this compound serves as an impurity of Remdesivir (CAS#: 1809249-37-3), a drug with therapeutic potential against various viral diseases. Its presence in the diastereomeric mixture of Remdesivir may provide insights into the drug's mechanism of action and help optimize its efficacy and safety profile.
Used in Drug Development:
The compound's unique structure and functional groups make it a valuable candidate for further drug development. It can be studied for its potential to interact with specific biological targets, which may lead to the discovery of new treatments for various diseases and conditions.

Upstream product

• 1355049-94-3 (3R,4R,5R)-2-(4-aminopyrrole-[2,1-f][1,2,4]-triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol 
• 1191237-68-9 (3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy) methyl)tetrahydrofuran-2-carbonitrile 
• 1191237-69-0 (2R,3R,4S,5R)?2?(4?aminopyrrolo[1,2?f][1,2,4]triazin?7?yl)?3,4?dihydroxy?5?(hydroxymethyl)tetrahydrofuran?2?carbonitrile 
• 1911578-98-7 (2S)-2-(((perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoic acid 2-ethylbutyl ester 
• 1770840-43-1 7-iodopyrrolo-[2,1-f][1,2,4]-triazin-4-amine 
• 1355357-49-1 (2R,3R,4R,5R)‐2‐{4‐aminopyrrolo[2,1‐f][1,2,4]triazin‐7‐yl}‐3,4‐bis(benzyloxy)‐5‐[(benzyloxy)methyl]tetrahydrofuran‐2‐carbonitrile 
• 946511-97-3 2-ethylbutyl (S)-2-aminopropanoate hydrochloride 
• 770-12-7 O-phenyl phosphorodichloridate 
• 159326-68-8 pyrrolo[2,1-f][1,2,4]triazin-4-amine 
• 14233-64-8 (3R,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-dihydro-furan-2-one 
• 16838-89-4 2,3,5-tri-O-benzyl-D-ribofuranose 
• 1439900-56-7 (2S)-2-ethylbutyl 2-(((4-nitrophenoxy)(phenoxy)phosphoryl)amino)propanoate 
• 261909-49-3 phenyl(isopropoxy-L-alaninyl) phosphorochloridate 
• 1355049-92-1 2-ethylbutyl (2S)-2-{[chloro(phenoxy)phosphoryl]amino}propanoate 

Downstream Products

• 1911578-75-0 (2S)-2-ethylbutyl 2-(((R)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate 
• 1809249-37-3 (2S)-2-ethylbutyl 2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate 

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