1378349-95-1

Basic information

• Product Name: methyl 2,6-bis(bis(3-phenylprop-2-yn-1-yl)amino)hexanoate
• Synonyms: methyl 2,6-bis(bis(3-phenylprop-2-yn-1-yl)amino)hexanoate
• CAS NO: 1378349-95-1
• Molecular Weight: 616.803
• Mol File: 1378349-95-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2,6-bis(bis(3-phenylprop-2-yn-1-yl)amino)hexanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2,6-bis(bis(3-phenylprop-2-yn-1-yl)amino)hexanoate(1378349-95-1)
• EPA Substance Registry System: methyl 2,6-bis(bis(3-phenylprop-2-yn-1-yl)amino)hexanoate(1378349-95-1)

Safety Data

• Hazardous Substances Data: 1378349-95-1(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 13515-95-2 lysine methyl ester dihydrochloride 
• 536-74-3 phenylacetylene 

Relevant articles and documents

Site-specific modification of amino acids and peptides by aldehyde-alkyne-amine coupling under ambient aqueous conditions

A highly efficient method for the direct, site-specific functionalization of amino acids and peptides, under ambient conditions, is described. In aqueous, nearly solvent-free conditions, copper(I) chloride catalyzed the aldehyde-alkyne-amine (A3) coupling of amino acids to form dipropargylated products in moderate to excellent yields. The propargylamine functionality provides a convenient handle for further structural modifications, demonstrated by a subsequent one-pot deprotection and click reaction and a solution-phase peptide coupling.