1418021-43-8

Basic information

• Product Name: C₂₄H₃₁NO₃
• CAS NO: 1418021-43-8
• Molecular Weight: 381.515
• Mol File: 1418021-43-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₄H₃₁NO₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₃₁NO₃(1418021-43-8)
• EPA Substance Registry System: C₂₄H₃₁NO₃(1418021-43-8)

Safety Data

• Hazardous Substances Data: 1418021-43-8(Hazardous Substances Data)

Upstream product

• 35794-11-7 3,5-dimethylpiperidine 
• 1426148-73-3 C₁₇H₁₄O₃ 
• 622-47-9 4-tolylacetic acid 
• 700-44-7 6-methoxysalicylaldehyde 

Relevant articles and documents

Small molecule amides as potent ROR-γ selective modulators

The structure-activity relationship study of a diphenylpropanamide series of ROR-γ selective modulators is reported. Compounds were screened using chimeric receptor Gal4 DNA-binding domain (DBD)-NR ligand binding domain cotransfection assay in a two-step format. Three different regions of the scaffold were modified to assess the effects on repression of ROR-γ transcriptional activity and potency. The lead compound 1 exhibits modest mouse pharmacokinetics and an acceptable in vitro profile which makes it a suitable in vivo probe to interrogate the functions of ROR-γ in animal models of disease.