1476-39-7Relevant articles and documents
Renewable Self-Blowing Non-Isocyanate Polyurethane Foams from Lysine and Sorbitol
Clark, James H.,Farmer, Thomas J.,Ingram, Ian D. V.,Lie, Yann,North, Michael
, p. 4265 - 4271 (2018)
Copolymerisation of a sorbitol-derived bis-carbonate with simple diamines, including cadaverine that was sustainably produced from lysine, under solvent-free conditions was shown to produce rigid foams. Thermogravimetric analysis carried out in tandem with infrared spectroscopy of the released gases confirmed that the foaming agent was carbon dioxide produced during the polymerisation process itself. Such a bio-based foam, being made under mild conditions from stable, benign precursors, with no toxic isocyanates, has great potential application for both thermal insulation and packaging.
Organic catalytic L - lysine chemical decarboxylation preparation 1, 5 - pentanediamine method (by machine translation)
-
Paragraph 0102-0107, (2020/06/17)
The invention provides an organic catalytic L - lysine chemical decarboxylation preparation 1, 5 -pentanediamine, and belongs to the field 1 and 5 -pentanediamine preparation methods. The method comprises L - lysine hydrochloride as a starting raw material, adding an alkali solution, carrying out neutralization reaction at room temperature, adding a solvent or L - lysine as a starting raw material, adding a solvent, adding hydrochloric acid and stirring reaction in an aqueous phase, stirring and reacting the solvent and washing with a solvent and obtaining 1 g 5 - pentanediamine. The method has the advantages of mild reaction conditions, simple operation, cheap and easily available catalyst and solvent, recyclable reutilization, low production cost, environmental friendliness, high product yield and suitability for large-scale preparation 1 and 5 - pentanediamine products. (by machine translation)
Rapid Conventional and Microwave-Assisted Decarboxylation of L-Histidine and Other Amino Acids via Organocatalysis with R-Carvone under Superheated Conditions
Jackson, Douglas M.,Ashley, Robert L.,Brownfield, Callan B.,Morrison, Daniel R.,Morrison, Richard W.
, p. 2691 - 2700 (2015/12/18)
This article reports a new methodology taking advantage of superheated chemistry via either microwave or conventional heating for the facile decarboxylation of alpha amino acids using the recoverable organocatalyst, R-carvone. The decarboxylation of amino acids is an important synthetic route to biologically active amines, and traditional methods of amino acid decarboxylation are time consuming (taking up to several days in the case of L-histidine), are narrow in scope, and make use of toxic catalysts. Decarboxylations of amino acids including L-histidine occur in just minutes while replacing toxic catalysts with green catalyst, spearmint oil. Yields are comparable to or exceed previous methods and purification of product ammonium chloride salts is aided by an isomerization reaction of residual catalyst to phenolic carvacrol. The method has been shown to be effective for the decarboxylations of a range of natural, synthetic, and protected amino acids.
