1484-26-0

Basic information

• Product Name: 3-BENZYLOXYANILINE
• Synonyms: Benzenamine, 3-(phenylmethoxy)-;M-(BENZYLOXY)ANILINE;3-BENZYLOXYANILINE;AKOS BBB/398;AKOS BC-2549;TIMTEC-BB SBB000388;3-Aminophenyl benzyl ether;3-(benzyloxy)phenylamine
• CAS NO: 1484-26-0
• Molecular Formula: C₁₃H₁₃NO
• Molecular Weight: 199.25
• EINECS: 216-056-6
• Product Categories: Anilines, Aromatic Amines and Nitro Compounds;Amines;C11 to C38;Nitrogen Compounds
• Mol File: 1484-26-0.mol
• Article Data: 38

Chemical Properties

• Melting Point: 63-67 °C(lit.)
• Boiling Point: 362.6 °C at 760 mmHg
• Flash Point: 184.4 °C
• Appearance: Pale brown/Solid
• Density: 1.129 g/cm³
• Vapor Pressure: 1.91E-05mmHg at 25°C
• Refractive Index: 1.616
• Storage Temp.: 2-8°C
• Solubility: soluble in Methanol
• PKA: 4.17±0.10(Predicted)
• CAS DataBase Reference: 3-BENZYLOXYANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BENZYLOXYANILINE(1484-26-0)
• EPA Substance Registry System: 3-BENZYLOXYANILINE(1484-26-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• RIDADR: 2811
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 1484-26-0(Hazardous Substances Data)

Usage

Chemical Properties

Beige to tan powder

Synthesis Reference(s)

Tetrahedron Letters, 23, p. 147, 1982 DOI: 10.1016/S0040-4039(00)86770-2

InChI:InChI=1/C13H13NO/c14-12-7-4-8-13(9-12)15-10-11-5-2-1-3-6-11/h1-9H,10,14H2

Upstream product

• 24318-00-1 3-(benzyloxy)nitrobenzol 
• 53087-13-1 3-(benzyloxy)phenyl bromide 
• 100-39-0 benzyl bromide 
• 99-65-0 meta-dinitrobenzene 
• 100-51-6 benzyl alcohol 
• 149507-31-3 tert-butyl (3-(benzyloxy)phenyl)carbamate 
• 19962-06-2 tert-butyl 3-hydroxyphenylcarbamate 
• 591-27-5 m-Hydroxyaniline 
• 100-44-7 benzyl chloride 
• 24318-02-3 1-(benzyloxy)-3-chlorobenzene 
• 621-42-1 meta-hydroxyacetanilide 
• 554-84-7 meta-nitrophenol 
• 107826-08-4 3-azidophenyl benzyl ether 
• 949-38-2 1-(benzyloxy)-2-chlorobenzene 

Downstream Products

• 55251-31-5 3-Benzyloxytrifluoromethanesulfonanilid 
• 17825-16-0 diethyl <<3-(benzyloxy)anilino>methylene>malonate 
• 199165-91-8 [(3-Benzyloxy-phenyl)-tert-butoxycarbonylmethyl-amino]-acetic acid tert-butyl ester 
• 438590-23-9 dimethyl 7-benzyloxyquinoline-2,4-dicarboxylate 
• 918666-96-3 4-(3-benzyloxy-phenylsulfamoyl)-benzoic acid 
• 162374-56-3 N-(3-Benzyloxy-phenyl)-2-chloro-4-nitro-thiobenzamide 
• 162374-68-7 5-benzyloxy-2-(2-chloro-4-nitrophenyl)benzothiazole 
• 172429-69-5 3-benzyloxy-8,9-methylenedioxyphenanthridine 
• 172429-68-4 N-(2-chloro-4,5-methylenedioxybenzyl)-3-benzyloxyaniline 
• 749922-33-6 5-{[(3-benzyloxy)phenylimino]methyl}-2,2-dimethyl-[1,3]-dioxane-4,6-dione 
• 117174-83-1 (3-benzyloxy-phenyl)thiourea 
• 206559-36-6 1-(benzyloxy)-3-isothiocyanatobenzene 
• 205935-12-2 N-(3-Benzyloxy-phenyl)-guanidine 
• 113-00-8 guanidine nitrate 

Relevant articles and documents

Substituted diarylurea derivative as well as preparation method and application thereof

The invention relates to a substituted diarylurea derivative as well as preparation and application thereof. Specifically, the invention discloses a compound with a formula (I) or an optical isomer, a cis-trans-isomer or a pharmaceutically acceptable salt thereof, and a preparation method thereof, wherein the definition of each substituent group in the general formula is described in the specification and claims. The invention further discloses a composition containing the compound and application of the composition. The compound disclosed by the invention has excellent anti-cancer activity on HepG2 liver cancer cells, MGC 803 gastric cancer cells, MCF 7 breast cancer cells and the like, and has a good inhibition effect on the growth of human umbilical vein endothelial cells (HUVEC).

Microballs Containing Ni(0)Pd(0) Nanoparticles for Highly Selective Micellar Catalysis in Water

Both Ni(0) complexes and nanoparticles (NPs) are unstable in water, which poses a significant hindrance to their application in aqueous synthetic catalysis. To overcome these barriers, ligated Ni(0) nanoparticles (diameter 1 nm) containing a minimum amount of Pd(0) in the microballs formed of amphiphile PS-750-M are developed and applied in the highly selective carbamate cleavage. Selectivity and functional group tolerance are thoroughly investigated. Control experiments revealed the importance of an individual component of the nanocatalyst. Use of our proline-based amphiphile PS-750-M is critical for achieving microball architecture, the stability of nanoparticles, and desired catalytic activity. Once formed, microballs can be isolated and stored at ambient temperature. Catalyst is thoroughly characterized by X-ray photoelectron spectroscopy, scanning electron microscopy, high-resolution transmission electron microscopy, thermogravimetric analysis, infrared, and cyclic voltammetry. For selective catalysis, zero oxidation state of both Ni and Pd is crucial. On the basis of catalyst characterization and control experiments, the plausible reaction mechanism is proposed.

Enantioselective Visible-Light-Mediated Formation of 3-Cyclopropylquinolones by Triplet-Sensitized Deracemization

3-Allyl-substituted quinolones undergo a triplet-sensitized di-π-methane rearrangement reaction to the corresponding 3-cyclopropylquinolones upon irradiation with visible light (λ=420 nm). A chiral hydrogen-bonding sensitizer (10 mol %) was shown to promote the reaction enantioselectively (88–96 % yield, 32–55 % ee). Surprisingly, it was found that the enantiodifferentiation does not occur at the state of initial product formation but that it is the result of a deracemization event. The individual parameters that control the distribution of enantiomers in the photostationary state have been identified.