151990-28-2Relevant articles and documents
Total Synthesis of Thymosin β4, 3. Conventional Synthesis of the Fragment of Thymosin β4
Link, Peter,Voelter, Wolfgang
, p. 1000 - 1008 (2007/10/02)
As part of our total synthesis of thymosin β4, an optimized synthesis of the C-terminal part of thymosin β4 is described.Side chain functional residues of the tridecapeptide are masked by tert-butyl and the α-amino-acids residues are protected by the Z groups.The fully protected peptide derivative was obtained by WSCI/HOBt coupling of three fragments representing the segments , and . Key words: Thymosin β4; fragment ; peptide; solution synthesis; thymosins.