17302-37-3

Basic information

• Product Name: Dimethyldecane, 2,2-
• Synonyms: Dimethyldecane, 2,2-
• CAS NO: 17302-37-3
• Molecular Formula: C₁₂H₂₆
• Molecular Weight: 170.33
• Product Categories: Aliphatics, Miscellaneous Reagents
• Mol File: 17302-37-3.mol
• Article Data: 11

Chemical Properties

• Melting Point: -50.8°C (estimate)
• Boiling Point: 201°C
• Flash Point: 70.1°C
• Appearance: /
• Density: 0.7406
• Vapor Pressure: 0.467mmHg at 25°C
• Refractive Index: 1.4169
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: Dimethyldecane, 2,2-(CAS DataBase Reference)
• NIST Chemistry Reference: Dimethyldecane, 2,2-(17302-37-3)
• EPA Substance Registry System: Dimethyldecane, 2,2-(17302-37-3)

Safety Data

• Hazardous Substances Data: 17302-37-3(Hazardous Substances Data)

Usage

Description

Dimethyldecane, 2,2is a decane isomer, which is a branched-chain alkane with the molecular formula C12H26. It is characterized by its two methyl groups attached to the second carbon atom in the chain. Dimethyldecane, 2,2is known for its unique chemical properties and structural configuration, making it a versatile component in various applications.

Uses

Used in Pharmaceutical Industry:
Dimethyldecane, 2,2is used as a key component in the synthesis of various pharmaceutical compounds. Its unique structural properties allow it to serve as an intermediate or building block in the development of new drugs, contributing to the advancement of medical treatments.
Used in Drug Manufacturing:
In the manufacture of drugs, Dimethyldecane, 2,2plays a crucial role as a raw material or precursor in the production process. Its compatibility with other chemical compounds and its ability to undergo various chemical reactions make it an essential ingredient in the formulation of different medications.

Synthesis Reference(s)

Synthesis, p. 662, 1974 DOI: 10.1055/s-1974-23397

InChI:InChI=1/C12H26/c1-5-6-7-8-9-10-11-12(2,3)4/h5-11H2,1-4H3

Upstream product

• 111-66-0 oct-1-ene 
• 630-19-3 pivalaldehyde 
• 94-36-0 dibenzoyl peroxide 
• 629-27-6 1-Iodooctane 
• 594-19-4 tert.-butyl lithium 
• 84718-85-4 (+/-)-2,2-dimethyl-3,4-decadiene 
• 3386-35-4 1-octyl p-toluenesulfonate 
• 106-99-0 buta-1,3-diene 
• 111-83-1 1-bromo-octane 
• 677-22-5 tert-butylmagnesium chloride 
• 507-20-0 tertiary butyl chloride 
• 111-85-3 n-chlorooctane 
• 4911-58-4 5,5-dimethyl-hex-1-en-3-yne 
• 463-11-6 1-Fluoro-octane 

Relevant articles and documents

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Copper-Catalyzed Regioselective Hydroalkylation of 1,3-Dienes with Alkyl Fluorides and Grignard Reagents

Copper complexes generated in situ from CuCl2, alkyl Grignard reagents, and 1,3-dienes play important roles as catalytic active species for the 1,2-hydroalkylation of 1,3-dienes by alkyl fluorides through C-F bond cleavage. The alkyl group is introduced to an internal carbon atom of the 1,3-diene regioselectively, thus giving rise to the branched terminal alkene product. Making the switch: A copper-hydride species, generated by the treatment of a copper salt with alkyl Grignard reagents, catalyzes the 1,2-hydroalkylation of 1,3-dienes by alkyl fluorides and Grignard reagents. The alkyl group of the alkyl fluoride is selectively introduced to an internal carbon atom of the 1,3-diene and the Grignard reagent acts as hydride source to give the branched terminal alkene, even in the presence of alkenes and alkynes.

The cobalt-catalyzed cross-coupling reaction of alkyl halides with alkyl Grignard reagents: A new route to constructing quaternary carbon centers

The cross-coupling of alkyl (pseudo)halides with alkyl Grignard reagents is catalyzed efficiently by a cobalt(II) chloride-lithium iodide-1,3-diene catalytic system, which provides a new synthetic tool for constructing sp 3 carbon chains. This system is particularly useful for creating quaternary carbon centers via the use of tertiary alkyl Grignard reagents. Various functional groups including esters, amides and carbamates are well tolerated.