173542-31-9Relevant articles and documents
Photocyclization reactions of epoxy nitriles via carbonyl ylides. Formation of spiroketals, spiroethers, and a spirolactone
Kotera,Ishii,Sakamoto
, p. 1621 - 1628 (1995)
Photocyclization reactions (λ = 254 nm) of λ-methyl δ-(4-hydroxybutyl) and δ-(4-hydroxypentyl) α,β-unsaturated γ,δ-epoxy nitriles gave spiroketals and spiroethers diastereoselectively, whereas reaction of δ-(6- hydroxyhexyl) nitrile afforded no cyclization product. In addition, photocyclization of nitrile bearing a carboxyl group in the δ-side-chain afforded spirolactone.