2009-84-9 Usage
Description
2-(6-Chlorohexyloxy)tetrahydro-2H-pyran is a substituted pyran, which is a type of heterocyclic compound consisting of a six-membered ring with one oxygen atom and five carbon atoms. The presence of a chloro group attached to a hexyloxy chain in the 6-position of the pyran ring gives this compound unique chemical properties and potential applications in various fields.
Uses
Used in Chemical Synthesis:
2-(6-Chlorohexyloxy)tetrahydro-2H-pyran is used as an intermediate in the synthesis of other organic compounds, particularly in the preparation of 2-(6-isothiocyanatohexyloxy)-tetrahydro-2H-pyran. 2-(6-CHLOROHEXYLOXY)TETRAHYDRO-2H-PYRAN& can be further utilized in the development of pharmaceuticals, agrochemicals, or other specialty chemicals that require the specific structural features provided by the chloro and hexyloxy groups.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-(6-chlorohexyloxy)tetrahydro-2H-pyran may be used as a building block for the development of new drugs with potential therapeutic applications. The chloro and hexyloxy functionalities can be exploited to create molecules with specific biological activities, such as modulating cellular signaling pathways or interacting with target proteins.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, 2-(6-chlorohexyloxy)tetrahydro-2H-pyran can be employed as a precursor for the synthesis of new pesticides, herbicides, or insecticides. The unique structural features of this compound may contribute to the development of more effective and environmentally friendly agrochemicals.
Used in Specialty Chemicals:
2-(6-Chlorohexyloxy)tetrahydro-2H-pyran may also find applications in the production of specialty chemicals for various industries, such as materials science, coatings, or adhesives. 2-(6-CHLOROHEXYLOXY)TETRAHYDRO-2H-PYRAN&'s properties can be tailored to create innovative products with improved performance characteristics.
Check Digit Verification of cas no
The CAS Registry Mumber 2009-84-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,0,0 and 9 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2009-84:
(6*2)+(5*0)+(4*0)+(3*9)+(2*8)+(1*4)=59
59 % 10 = 9
So 2009-84-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H21ClO2/c12-8-4-1-2-5-9-13-11-7-3-6-10-14-11/h11H,1-10H2
2009-84-9Relevant articles and documents
Dihydrotestosterone derivatives: Relative binding affinity versus affinity purification
Stobaugh, Mark E.,Blickenstaff, Robert T.
, p. 581 - 585 (1991)
Mono esters of a homologous series of diacids of dihydrotestosterone were synthesized and converted to the corresponding n-butyl amides. The relative binding affinities of these amides to androgen receptor were compared with the degree of purification of rat prostate androgen receptor by affinity columns prepared by linking the steroidal acid to ammo Sepharose. There was good correlation between binding of the amide model to androgen receptor and the extent of purification by the affinity resin.
Method for preparing 8 -methyldialdehyde
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Paragraph 0044-0047; 0054-0057; 0064-0067, (2021/11/03)
To the preparation method of 8 - chloro 6 - hexanol, the hydroxyl is firstly protected with the dihydropyran under the catalysis of p-toluenesulfonic acid, and -1 -chloro 6 -hexyl tetrahydropyranyl is obtained. 6 -chloro -hexyl tetrahydropyranyl ether is reacted with magnesium chips to form a formative reagent and reacted with 1 - bromo -2 - methyl - butane under the catalysis of cuprous bromide to obtain the intermediate 8 - methyl -tetrahydropyran ether. The intermediates do not need to be purified, and the hydroxyl group is removed directly under acidic conditions to obtain 8 - methyl -1 - sunflower. Finally, 2, 2, 6 and 6 - tetramethylpiperidine are oxidized to obtain the product 8 - methyldialdehyde. The synthesis process uses common reagents, is low in cost, mild in reaction conditions and high in yield, is suitable for large-scale industrial production, and has a good application prospect in the field of food additives.
ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS
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Page/Page column 123-124; 142-143, (2021/05/21)
The disclosure relates to anti-cancer compounds which are anti-cancer PARP inhibitors of formula Al, A2, A3 or A4 conjugated by a linker to a steroid, whereby the steroid targets the conjugate to the nucleus, as well as to methods for their preparation and use. (I)
