17876-99-2 Usage
Description
(4-chlorobenzyl)(trimethyl)silane, with the molecular formula C11H15ClSi, is a colorless to light yellow liquid at room temperature. It is a silane compound characterized by a silicon atom bonded to carbon and hydrogen atoms, along with a chlorobenzyl group and three trimethylsilyl groups. This unique structure endows it with special reactivity, making it a valuable component in various chemical reactions.
Uses
Used in Organic Synthesis:
(4-chlorobenzyl)(trimethyl)silane is used as a reagent in organic synthesis for its unique reactivity, which allows it to participate in a variety of chemical reactions.
Used as a Protective Group for Alcohols:
In the field of organic chemistry, (4-chlorobenzyl)(trimethyl)silane serves as a protective group for alcohols, safeguarding them from unwanted reactions during the synthesis process.
Used in Pharmaceutical Synthesis:
(4-chlorobenzyl)(trimethyl)silane is utilized as a precursor in the synthesis of pharmaceuticals, contributing to the development of new drugs and medicines.
Used in Agrochemical Synthesis:
(4-chlorobenzyl)(trimethyl)silane is also employed in the synthesis of agrochemicals, playing a role in the production of chemicals used in agriculture to protect crops and enhance their growth.
Used as a Cross-Coupling Reagent:
(4-chlorobenzyl)(trimethyl)silane is used as a cross-coupling reagent, facilitating the formation of carbon-carbon bonds in organic synthesis, which is crucial for constructing complex molecular structures.
Used in the Production of Specialty Materials:
This versatile compound is also used in the production of specialty materials, where its unique properties can be harnessed to create materials with specific characteristics for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 17876-99-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,8,7 and 6 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 17876-99:
(7*1)+(6*7)+(5*8)+(4*7)+(3*6)+(2*9)+(1*9)=162
162 % 10 = 2
So 17876-99-2 is a valid CAS Registry Number.
17876-99-2Relevant articles and documents
Murahashi Cross-Coupling at ?78 °C: A One-Pot Procedure for Sequential C?C/C?C, C?C/C?N, and C?C/C?S Cross-Coupling of Bromo-Chloro-Arenes
Sinha, Narayan,Heijnen, Dorus,Feringa, Ben L.,Organ, Michael G.
supporting information, p. 9180 - 9184 (2019/07/04)
The coupling of organolithium reagents, including strongly hindered examples, at cryogenic temperatures (as low as ?78 °C) has been achieved with high-reactivity Pd-NHC catalysts. A temperature-dependent chemoselectivity trigger has been developed for the selective coupling of aryl bromides in the presence of chlorides. Building on this, a one-pot, sequential coupling strategy is presented for the rapid construction of advanced building blocks. Importantly, one-shot addition of alkyllithium compounds to Pd cross-coupling reactions has been achieved, eliminating the need for slow addition by syringe pump.
α,n-didehydrotoluenes by photoactivation of (chlorobenzyl) trimethylsilanes: An alternative to enyne-allenes cyclization
Protti, Stefano,Ravelli, Davide,Mannucci, Barbara,Albini, Angelo,Fagnoni, Maurizio
supporting information; experimental part, p. 8577 - 8580 (2012/09/22)
Doubly radical: A novel entry to ?,n-didehydrotoluene (DHT) diradicals is disclosed and proceeds through the photochemical activation of (chlorobenzyl)trimethylsilanes with chloride loss and elimination of the SiMe3+ group (see scheme). The products formed in solution are indicative of the intermediacy of the three isomers of the ?,n-DHT
SYNTHESIS OF SUBSTITUTED BENZYLTRIMETHYLSILANES FROM TETRAMETHYLAMMONIUM TETRAKIS(TRIMETHYLSILYLMETHYL)BORATE AND ARYL HALIDES
Bumagin, N. A.,Bykov, V. V.,Artamkina, G. A.,Beletskaya, I. P.
, p. 2417 (2007/10/02)
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