215667-88-2

Basic information

• Product Name: 4-iodo-1-(4-trifluoromethylphenyl)butanone
• Synonyms: 4-iodo-1-(4-trifluoromethylphenyl)butanone
• CAS NO: 215667-88-2
• Molecular Weight: 342.1
• Mol File: 215667-88-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-iodo-1-(4-trifluoromethylphenyl)butanone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-iodo-1-(4-trifluoromethylphenyl)butanone(215667-88-2)
• EPA Substance Registry System: 4-iodo-1-(4-trifluoromethylphenyl)butanone(215667-88-2)

Safety Data

• Hazardous Substances Data: 215667-88-2(Hazardous Substances Data)

Upstream product

• 402-51-7 4-(trifluoromethyl)phenylmagnesium bromide 
• 327617-82-3 4-chloro-1-(4-(trifluoromethyl)phenyl)butan-1-one 

Relevant articles and documents

New efficient nickel-catalyzed cross-coupling reaction between two Csp3 centers

The presence of a remote unsaturation (double bond, carbonyl group, cyano group) in an alkyl halide facilitates its cross-coupling reaction with various diorganozincs in the presence of Ni(acac)2 (7.5-10 mol % in THF/NMP mixtures). These results were used to develop a new general cross-coupling reaction between functionalized diorganozincs and alkyl iodides using m- or p-trifluoromethylstyrene as a reaction promotor and Ni(acac)2 as a catalyst (7.5-10 mol %; -35 °C, 5-10 h) leading to a broad range of polyfunctional cross-coupling products.