22865-49-2

Basic information

• Product Name: Benzene, 1-methyl-4-[(4-nitrophenyl)sulfinyl]-
• CAS NO: 22865-49-2
• Molecular Formula: C13H11NO3S
• Molecular Weight: 261.301
• Mol File: 22865-49-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methyl-4-[(4-nitrophenyl)sulfinyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methyl-4-[(4-nitrophenyl)sulfinyl]-(22865-49-2)
• EPA Substance Registry System: Benzene, 1-methyl-4-[(4-nitrophenyl)sulfinyl]-(22865-49-2)

Safety Data

• Hazardous Substances Data: 22865-49-2(Hazardous Substances Data)

Upstream product

• 456-27-9 4-nitrobenzenediazonium tetrafluoroborate 
• 106-45-6 para-thiocresol 
• 636-98-6 p-nitrobenzene iodide 
• 10381-71-2 p-tolyl allyl sulfoxide 
• 100-00-5 4-chlorobenzonitrile 
• 911820-09-2 3-[(4-methylphenyl)sulfinyl]propanoic acid tert-butyl ester 
• 22865-48-1 4-nitrophenyl 4-methylphenyl sulfide 

Downstream Products

• 882-33-7 diphenyldisulfane 
• 103-19-5 di(p-tolyl) disulfide 
• 22865-48-1 4-nitrophenyl 4-methylphenyl sulfide 
• 100-32-3 di(p-nitrophenyl) disulfide 
• 6873-55-8 p-tolylsulfinyl amide 

Relevant articles and documents

Preparation method for sulfoxide compound

The invention discloses a preparation method for a sulfoxide compound and belongs to the technical field of catalysis. The invention provides a new green and environment-friendly method for efficiently synthesizing the sulfoxide compound. Under the action of catalyst, thiophenol, aryl diazonium compound and oxidizing agent are directly oxidized into the sulfoxide compound under the condition of light radiation, wherein cercosporin is served as the catalyst. According to the method disclosed by the invention, cercosporin is served as the catalyst; catalyzing condition is mild; catalysis can beperformed under room temperature and radiation of visible light; catalytic activity of catalyst is high; the catalyst can high-selectively catalyze synthesis of sulfoxide compound; with a trace amountof catalyst, yield can reach up to above 70%. The preparation method disclosed by the invention has the advantages of simple and easily acquired photocatalyst and substrate raw materials, environmental protection, low cost, large batch production and bright application prospect.

Selective deprotection of phenolic polysulfonates

Nosylates of phenols can be selectively deprotected by thiocresol anions in DMSO. Successful deprotection can be accomplished in molecules containing aryl-appended halides, ethers, aldehydes, alkanesulfonates or arylsulfonates. Nosylate deprotection is accomplished by the CS bond rupture which is believed to proceed by nucleophilic aromatic substitution.

Aryl sulfoxides via palladium-catalyzed arylation of sulfenate anions

(Chemical Equation Presented) Palladium-catalyzed arylation of sulfenate anions generated from β-sulfinyl esters can take place under biphasic conditions. This hitherto unknown reaction provides a simple, mild, and efficient route to aryl sulfoxides in good yields. The development of a new pseudo-domino type I procedure involving a sulfinylation followed by a Mirozoki-Heck coupling is also described.